A novel approach combining network pharmacology and experimental validation to study the protective effect of ginsenoside Rb1 against cantharidin‐induced …

L Xiong, K Lin, T He, X Liu, R Yuan… - Basic & Clinical …, 2024 - Wiley Online Library
Cantharidin (CTD) is a widely used anticancer compound, but its clinical use is mainly
limited due to hepatotoxicity. Ginsenoside Rb1 (GRb1) shows potential hepatoprotective …

[HTML][HTML] Network pharmacology integrated with molecular docking technology to reveal the potential mechanism of Shuganfang against drug-induced liver injury

Y Wang, X Chen, Y Wang, H Zhong, L Liu, Y Ye - Medicine, 2023 - journals.lww.com
This study aimed to investigate the active composition and mechanism of the Shuganfang
(SGF) in treating drug-induced liver injury (DILI) using network pharmacology and molecular …

Active compounds screening and hepatoprotective mechanism of Shuganning injection based on network pharmacology and experimental validation

Q Wang, X Duan, S Li, H Lai, W Cheng… - Natural Product …, 2022 - journals.sagepub.com
Objective: The study aimed to analyze the core active compounds and the potential
mechanism of Shuganning injection (SGNI) through network pharmacology with biological …

The Effect of Dried Lemon Peel on Chronic Immobilization-Induced Liver Damage in Male Wistar Rats

R Amini, M Asle-Rousta - Iranian Journal of Endocrinology and …, 2022 - ijem.sbmu.ac.ir
مقدمه Page 1 رتکد ینیما میحر 3 ، رتکد صا همودعم اتسور 3 3 تسيز هورگ ،ناريا ،ناجنز ،یملاسا دازآ
هاگشناد ،ناجنز دحاو ،یسانش 3 ،یملاسا دازآ هاگشناد ،ناجنز دحاو ،يژولويزیف هورگ ،ناريا ،ناجنز ن …

[PDF][PDF] Differentiated modulation of signaling molecules AMPK and SIRT1 in experimentally drug-induced hepatocyte injury.

LN Wojnarova, NK Canova, M Arora… - Biomedical Papers of …, 2023 - biomed.papers.upol.cz
Aim. Currently available medicines have little to offer in terms of supporting the regeneration
of injured hepatic cells. Previous experimental studies have shown that resveratrol and …

[PDF][PDF] Effect of bergenin on D-galactosamine-induced acute liver injury in rats

J XU, Y GAO, Y JI - Chinese Journal of Public Health, 2022 - zgggws.com
Objective To study protective effect and mechanism of bergenin on D-galactosamine (D-
GalN)-induced acute liver injury in rats. Methods Totally 60 Sprague-Dawley (SD) rats were …

[PDF][PDF] 岩白菜素对D-GalN 诱导大鼠急性肝损伤影响

徐杰, 高雅, 吉燕萍, 连苑宇, 张可锋 - 中国公共卫生, 2022 - zgggws.com
岩白菜素对D-GalN 诱导大鼠急性肝损伤影响 Page 1 • 实验研究 • 岩白菜素对D-GalN 诱导大鼠
急性肝损伤影响* 徐杰,高雅,吉燕萍,连苑宇,张可锋 [摘 要]目的 了解岩白菜素对D-GalN 诱导急性肝 …

Amelioration of Hepatotoxicity Accompanied to Cyclophosphamide Therapy by Citrus aurantium L. Peel in Wistar Rats

MS Halaby, IH Badawy, AS Maghraby… - Egyptian Journal of …, 2022 - journals.ekb.eg
The use of cyclophosphamide as a chemotherapy drug for treatment of many malignancies
is mostly accompanied by hepatotoxicity. So, the present study aimed to investigate the …

Hugan Buzure granule ameliorates immune liver injury through the EGFR/Ras/PI3K/AKT signaling pathway: A network pharmacology study and experimental …

Z Han, W Song, Y Luo, M Xiao… - Journal of Chinese …, 2024 - search.ebscohost.com
Hugan Buzure granule (HBG) is a traditional prescription in Uygur medicine that is known for
its hepatoprotective properties. In a previous study, the authors have investigated the …

Investigation of the mechanism of traditional Mongolian medicine Gurigumu-13 pill for treating acetaminophen-induced liver injury using a network pharmacology and …

Y Xue-Miao, BO Yu-Kun, Y Dan, Z Guo-Jun… - Chinese Journal of …, 2022 - Elsevier
Abstract Gurigumu-13 Pill (GRGM) is a traditional Mongolian medicine prescription that has
a liver-protective effect. However, the underlying therapeutic mechanisms of GRGM for …