Background Phosphate binders are used to reduce positive phosphate balance and to lower
serum phosphate levels for people with chronic kidney disease (CKD) with the aim to …

Klotho is a critical protein that protects the kidney. Klotho is severely downregulated in
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …

Background: Nicotinamide (NAM) has been proposed as an alternative treatment to
phosphate binders for hyperphosphataemia in chronic kidney disease. Methods: The …

Vascular calcification is highly prevalent in patients with chronic kidney disease (CKD) and
increases mortality in those patients. Impaired calcium and phosphate homeostasis …

Background. It remains unclear which phosphate binders should be preferred for
hyperphosphatemia management in chronic kidney disease (CKD). Methods. We performed …

Background Treatment of hyperphosphataemia is the primary goal of chronic kidney disease–
mineral and bone disorder (CKD-MBD) management. This post hoc analysis of a …

Phosphate binders are among the most common medications prescribed to patients with
kidney failure receiving dialysis and are often used in advanced chronic kidney disease …

Background: The correlation between soluble Klotho (sKlotho) level and vascular
calcification (VC) in patients with chronic kidney disease (CKD) remains controversial. Using …

Background In hemodialysis patients, high levels of Fibroblast Growth Factor 23 (FGF23)
predict mortality. Our study was designed to test whether the control of serum phosphate is …

Progression of chronic kidney disease (CKD) is inevitable. However, the last decade has
witnessed tremendous achievements in this field. Today we are optimistic; the dream of …