In accordance with the recommendations of, amongst others, the Surviving Sepsis
Campaign and the recently published European treatment guidelines for hospital-acquired …

Multiple organ dysfunction syndrome (MODS), defined as the presence of altered organ
function in an acutely ill patient such that homeostasis cannot be maintained without …

Background The association between antithrombin use and mortality in patients with sepsis‐
associated disseminated intravascular coagulation (DIC) remains controversial. Objectives …

Abstract Models of sepsis have been instructive in understanding the sequence of events in
animals and, to an extent, in humans with sepsis. Events developing early in sepsis suggest …

Nosocomial pneumonia, or hospital-acquired pneumonia (HAP), and ventilator-associated
pneumonia (VAP) are important health problems worldwide, with both being associated with …

Background Previous studies showed higher sepsis mortality rates in Brazil compared to
other developed or developing countries. Moreover, another trial demonstrated an …

Our aim was to assess the incidence, characteristics, aetiology, risk factors and mortality of
acute respiratory distress syndrome (ARDS) in intensive care unit (ICU) patients with …

Background: Intensive care unit-acquired pneumonia (ICU-AP) is a severe complication in
patients admitted to the ICU. Lymphocytopenia is a marker of poor prognosis in patients with …

Given the enormous estimated burden of respiratory virus infections worldwide, a substantial
number of research priorities exist in order to better understand their epidemiology …

Background. Most studies have reported that corticosteroid therapy adversely influences
influenza-related outcomes. Methods. Electronic databases were searched from inception to …