Human melioidosis

I Gassiep, M Armstrong, R Norton - Clinical microbiology reviews, 2020 - Am Soc Microbiol
The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

Within-Host Evolution of Burkholderia pseudomallei during Chronic Infection of Seven Australasian Cystic Fibrosis Patients

LT Viberg, DS Sarovich, TJ Kidd, JB Geake, SC Bell… - MBio, 2017 - Am Soc Microbiol
Cystic fibrosis (CF) is a genetic disorder characterized by progressive lung function decline.
CF patients are at an increased risk of respiratory infections, including those by the …

Genomic Insights Into the Melioidosis Pathogen, Burkholderia pseudomallei

EP Price, BJ Currie, DS Sarovich - Current Tropical Medicine Reports, 2017 - Springer
Abstract Purpose of Review Genomics has fundamentally transformed our understanding of
infectious diseases. Here, we provide an overview of the insights gained from genomic …

Vibrio cholerae genomic diversity within and between patients

I Levade, Y Terrat, JB Leducq, AA Weil… - Microbial …, 2017 - microbiologyresearch.org
Cholera is a severe, water-borne diarrhoeal disease caused by toxin-producing strains of
the bacterium Vibrio cholerae. Comparative genomics has revealed 'waves' of cholera …

Tracing melioidosis back to the source: using whole-genome sequencing to investigate an outbreak originating from a contaminated domestic water supply

E McRobb, DS Sarovich, EP Price… - Journal of clinical …, 2015 - Am Soc Microbiol
Melioidosis, a disease of public health importance in Southeast Asia and northern Australia,
is caused by the Gram-negative soil bacillus Burkholderia pseudomallei. Melioidosis is …

Multilocus variable-number tandem-repeat analysis of Yersinia ruckeri confirms the existence of host specificity, geographic endemism, and anthropogenic …

S Gulla, AC Barnes, TJ Welch… - Applied and …, 2018 - Am Soc Microbiol
ABSTRACT A multilocus variable-number tandem-repeat analysis (MLVA) assay was
developed for epizootiological study of the internationally significant fish pathogen Yersinia …

[HTML][HTML] Phenotypic and genetic alterations of Burkholderia pseudomallei in patients during relapse and persistent infections

R Seng, R Phunpang, N Saiprom, A Dulsuk… - Frontiers in …, 2023 - frontiersin.org
The bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a severe
tropical disease associated with high mortality and relapse and persistent infections …

Whole-genome sequencing of Burkholderia pseudomallei isolates from an unusual melioidosis case identifies a polyclonal infection with the same multilocus …

EP Price, DS Sarovich, L Viberg, M Mayo… - Journal of clinical …, 2015 - Am Soc Microbiol
Twelve Burkholderia pseudomallei isolates collected over a 32-month period from a patient
with chronic melioidosis demonstrated identical multilocus sequence types (STs). However …

[HTML][HTML] Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei

C Chewapreecha, AE Mather, SR Harris… - Communications …, 2019 - nature.com
The environmental bacterium Burkholderia pseudomallei causes melioidosis, an important
endemic human disease in tropical and sub-tropical countries. This bacterium occupies …

Whole-genome sequencing of a quarter-century melioidosis outbreak in temperate Australia uncovers a region of low-prevalence endemicity

SNJ Chapple, DS Sarovich, MTG Holden… - Microbial …, 2016 - microbiologyresearch.org
Melioidosis, caused by the highly recombinogenic bacterium Burkholderia pseudomallei, is
a disease with high mortality. Tracing the origin of melioidosis outbreaks and understanding …