▪ Abstract Branching morphogenesis of the lung and differentiation of specialized cell
populations is dependent upon reciprocal interactions between epithelial cells derived from …

Surfactant protein A (SP-A) is a highly ordered, oligomeric glycoprotein that is secreted into
the airspaces of the lung by the pulmonary epithelium. The in vitro activities of protein …

The collectins family encompasses several collagenous Ca 2+-dependent defense lectins
that are described as pathogen recognition molecules. They play an important role in both …

The use of candidate genes has increased the ability to identify genetic factors involved in
diseases with complex and multifactorial etiology. The surfactant proteins (SP) A and D are …

The human surfactant protein (SP) A locus has been assigned to chromosome 10q22-q23
and consists of two very similar genes, SP-A1 and SP-A2, as well as a truncated …

LDL low-density lipoprotein (s) MLV multilamellar vesicles NBD N-(7-nitrobenz-2-oxa-1, 3-
diazol-4-yl) PC phosphatidylcholine PE phosphatidylethanolamine PG phosphatidylglycerol …

Introduction 3. Cell/tissue-specific expression of surfactant protein genes 4. Developmental
regulation of surfactant protein gene expression 5. Multifactorial regulation of surfactant …

The human SFTPA1 and SFTPA2 genes encode the surfactant protein A1 (SP-A1) and SP-
A2, respectively, and they have been identified with significant genetic and epigenetic …

Surfactant proteins A and D (SP-A and SP-D) are believed to participate in the pulmonary
host defense and the response to lung injury. In order to understand the effects of …

Surfactant protein (SP)-A gene transcription is stimulated by factors that increase cyclic AMP.
In the present study, we observed that three thyroid transcription factor-1 (TTF-1) binding …