Lung cancer in never smokers—a different disease

S Sun, JH Schiller, AF Gazdar - Nature Reviews Cancer, 2007 - nature.com
Although most lung cancers are a result of smoking, approximately 25% of lung cancer
cases worldwide are not attributable to tobacco use, accounting for over 300,000 deaths …

[HTML][HTML] Implications of the immune landscape in COPD and lung cancer: smoking versus other causes

E Taucher, I Mykoliuk, J Lindenmann… - Frontiers in …, 2022 - frontiersin.org
Cigarette smoking is reported in about one third of adults worldwide. A strong relationship
between cigarette smoke exposure and chronic obstructive pulmonary disease (COPD) as …

Lung cancer incidence in never smokers

HA Wakelee, ET Chang, SL Gomez… - Journal of Clinical …, 2007 - ascopubs.org
Purpose Lung cancer is a leading cause of cancer death worldwide. Although smoking
remains the predominant cause of lung cancer, lung cancer in never smokers is an …

Lung cancer in never smokers

GA Rivera, H Wakelee - Lung cancer and personalized medicine: current …, 2016 - Springer
Lung cancer is predominantly associated with cigarette smoking; however, a substantial
minority of patients with the disease have never smoked. In the US it is estimated there are …

EGFR tyrosine kinase inhibitors in lung cancer: an evolving story

LV Sequist, TJ Lynch - Annu. Rev. Med., 2008 - annualreviews.org
Drugs that target the epidermal growth factor receptor (EGFR) have had a major impact on
the treatment of non–small cell lung cancer (NSCLC). The use of these drugs has also …

Smoking history and epidermal growth factor receptor expression as predictors of survival benefit from erlotinib for patients with non–small-cell lung cancer in the …

GM Clark, DM Zborowski, P Santabárbara, K Ding… - Clinical lung cancer, 2006 - Elsevier
Background Erlotinib is an oral, reversible inhibitor of the HER1/epidermal growth factor
receptor (EGFR) tyrosine kinase. A survival advantage for erlotinib compared with placebo …

[HTML][HTML] Asian ethnicity is a favorable prognostic factor for overall survival in non-small cell lung cancer (NSCLC) and is independent of smoking status

SHI Ou, A Ziogas, JA Zell - Journal of Thoracic Oncology, 2009 - Elsevier
Background We previously showed that Asian ethnicity was an independent favorable
prognostic factor in non-small cell lung cancer (NSCLC). Many Asian NSCLC patients were …

Targeted therapies for lung cancer: clinical experience and novel agents

JE Larsen, T Cascone, DE Gerber… - The Cancer …, 2011 - journals.lww.com
Although lung cancer remains the leading cancer killer in the United States, recently a
number of developments indicate future clinical benefit. These include evidence that …

Nicotine and apoptosis

R Zeidler, K Albermann, S Lang - Apoptosis, 2007 - Springer
Cigarette smoking is associated with a plethora of different diseases. Nicotine is the
addictive component of cigarette but also acts onto cells of the non-neuronal system …

Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths

YL Wu, C Dudognon, E Nguyen, J Hillion… - Journal of cell …, 2006 - journals.biologists.com
The involvement of telomerase in cellular immortalization and senescence has often been
assessed by means of telomerase expression at the RNA level and quantification of …