Oxidative stress is the consequence of an overproduction of reactive oxygen species (ROS)
that exceeds the antioxidant defense mechanisms. Increased levels of ROS contribute to the …

Dual antiplatelet therapy (DAPT) has remained the cornerstone for management of acute
coronary syndrome (ACS) over the years. Clopidogrel has been the quintessential P2Y12 …

Background The problem of ischemic stroke (IS) has become increasingly important in
recent years, as it ranks first in the structure of disability and mortality, crowding out other …

Abstract Low Density Lipoprotein (LDL) and oxidized LDL (oxLDL) are major contributors to
atherogenesis, as endogenous antigens, via several receptors such as LOX 1. A PubMed …

LOX-1, ORL-1, or lectin-like oxidized low-density lipoprotein receptor 1 is a transmembrane
glycoprotein that binds and internalizes ox-LDL in foam cells. LOX-1 is the main receptor for …

Background Blood clots are living tissues that release inflammatory mediators including IL-
8/CXCL8 and MCP-1/CCL2. A deeper understanding of blood clots is needed to develop …

Background Psoriasis is a chronic inflammatory condition associated with coronary artery
disease risk. Uptake of oxidized low‐density lipoprotein by the lectin‐like low‐density …

Background: Several lines of evidence have supported small dense low-density lipoproteins
(sd-LDL) as a marker of cardiovascular disease. The present study assessed the …

Methods We enrolled 62 patients who underwent diagnostic coronary angiography (CAG)
and 30 healthy controls (21 men and nine women) and measured sLOX-1, troponin I, and …

Lectin-like oxidized low density lipoprotein-1 (Lox-1) is an endothelial scavenger receptor
for oxidized LDL. Several studies reported that Lox-1 is expressed by platelets and that in …