[HTML][HTML] A perfect fit: Bacteriophage receptor-binding proteins for diagnostic and therapeutic applications
Bacteriophages are the most abundant biological entity on earth, acting as the predators
and evolutionary drivers of bacteria. Owing to their inherent ability to specifically infect and …
and evolutionary drivers of bacteria. Owing to their inherent ability to specifically infect and …
[HTML][HTML] Evolutionary dynamics between phages and bacteria as a possible approach for designing effective phage therapies against antibiotic-resistant bacteria
With the increasing global threat of antibiotic resistance, there is an urgent need to develop
new effective therapies to tackle antibiotic-resistant bacterial infections. Bacteriophage …
new effective therapies to tackle antibiotic-resistant bacterial infections. Bacteriophage …
Bacteriophage therapy in aquaculture: Current status and future challenges
R Liu, G Han, Z Li, S Cun, B Hao, J Zhang, X Liu - Folia Microbiologica, 2022 - Springer
The escalation of antibiotic resistance has revitalized bacteriophage (phage) therapy.
Recently, phage therapy has been gradually applied in medicine, agriculture, food, and …
Recently, phage therapy has been gradually applied in medicine, agriculture, food, and …
Bacteriophages as drivers of bacterial virulence and their potential for biotechnological exploitation
K Schroven, A Aertsen, R Lavigne - FEMS microbiology reviews, 2021 - academic.oup.com
Bacteria-infecting viruses (phages) and their hosts maintain an ancient and complex
relationship. Bacterial predation by lytic phages drives an ongoing phage-host arms race …
relationship. Bacterial predation by lytic phages drives an ongoing phage-host arms race …
CRISPR systems: Novel approaches for detection and combating COVID-19
Abstract Type V and VI CRISPR enzymes are RNA-guided, DNA and RNA-targeting
effectors that allow specific gene knockdown. Cas12 and Cas13 are CRISPR proteins that …
effectors that allow specific gene knockdown. Cas12 and Cas13 are CRISPR proteins that …
[HTML][HTML] Crystal structure and functional implication of bacterial STING
Mammalian innate immune sensor STING (ST imulator of IN terferon G ene) was recently
found to originate from bacteria. During phage infection, bacterial STING sense c-di-GMP …
found to originate from bacteria. During phage infection, bacterial STING sense c-di-GMP …
[HTML][HTML] Potential utility of melatonin in deadly infectious diseases related to the overreaction of innate immune response and destructive inflammation: focus on …
DX Tan, R Hardeland - Melatonin Research, 2020 - melatonin-research.net
The high mortality of deadly virus infectious diseases including SARS, MERS, COVID-19,
and avian flu is often caused by the uncontrolled innate immune response and destructive …
and avian flu is often caused by the uncontrolled innate immune response and destructive …
Development of phage resistance in multidrug-resistant Klebsiella pneumoniae is associated with reduced virulence: a case report of a personalised phage therapy
J Li, B Yan, B He, L Li, X Zhou, N Wu, Q Wang… - Clinical Microbiology …, 2023 - Elsevier
Objectives Phage-resistant bacteria often emerge rapidly when performing phage therapy.
However, the relationship between the emergence of phage-resistant bacteria and …
However, the relationship between the emergence of phage-resistant bacteria and …
[HTML][HTML] Acinetobacter baumannii phages: past, present and future
Q Tu, M Pu, Y Li, Y Wang, M Li, L Song, M Li, X An… - Viruses, 2023 - mdpi.com
Acinetobacter baumannii (A. baumannii) is one of the most common clinical pathogens and
a typical multi-drug resistant (MDR) bacterium. With the increase of drug-resistant A …
a typical multi-drug resistant (MDR) bacterium. With the increase of drug-resistant A …
Sequence-function relationships in phage-encoded bacterial cell wall lytic enzymes and their implications for phage-derived product design
Phage (endo) lysins are thought to be a viable alternative to usual antibiotic chemotherapy
to fight resistant bacterial infections. However, a comprehensive view of lysins' structure and …
to fight resistant bacterial infections. However, a comprehensive view of lysins' structure and …