[HTML][HTML] Gut microbiota is a potential biomarker in inflammatory bowel disease

X Guo, C Huang, J Xu, H Xu, L Liu, H Zhao… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's
disease (CD), is characterized by relapse and remission alternately. It remains a great …

Disease-modifying anti-asthmatic drugs

M Lommatzsch, GG Brusselle, GW Canonica… - The Lancet, 2022 - thelancet.com
Drugs available for asthma treatment in the first decades of the 20th century
(sympathomimetic agents such as oral ephedrine, intravenous adrenaline, or inhaled …

Recent advances in clinical practice: advances in cross-sectional imaging in inflammatory bowel disease

J Rimola, J Torres, S Kumar, SA Taylor, T Kucharzik - Gut, 2022 - gut.bmj.com
Endoscopy remains the reference standard for the diagnosis and assessment of patients
with inflammatory bowel disease (IBD), but it has several important limitations. Cross …

[HTML][HTML] Ulcerative colitis: an update

JP Segal, JF LeBlanc, AL Hart - Clinical Medicine, 2021 - ncbi.nlm.nih.gov
Ulcerative colitis is a relapsing and remitting disease that is increasing in incidence and
prevalence. Management aims to achieve rapid resolution of symptoms, mucosal healing …

How do we predict a patient's disease course and whether they will respond to specific treatments?

B Verstockt, M Parkes, JC Lee - Gastroenterology, 2022 - Elsevier
Gastroenterologists will be all too familiar with the difficult decisions that managing
inflammatory bowel disease often presents. How aggressively should I treat this patient? Do …

Intestinal barrier healing is superior to endoscopic and histologic remission for predicting major adverse outcomes in inflammatory bowel disease: the prospective …

T Rath, R Atreya, J Bodenschatz, W Uter, CE Geppert… - Gastroenterology, 2023 - Elsevier
Background & Aims Endoscopic and histologic remission have emerged as key therapeutic
goals in the management of inflammatory bowel diseases (IBD) that are associated with …

Evolving short-and long-term goals of management of inflammatory bowel diseases: getting it right, making it last

C Le Berre, A Ricciuto, L Peyrin-Biroulet, D Turner - Gastroenterology, 2022 - Elsevier
Short-and long-term treatment targets in inflammatory bowel diseases (IBDs) evolved during
the last decade, shifting from symptom control to endoscopic healing and patient-centered …

Biopsy and blood-based molecular biomarker of inflammation in IBD

C Argmann, R Hou, RC Ungaro, H Irizar, Z Al-Taie… - Gut, 2023 - gut.bmj.com
Objective IBD therapies and treatments are evolving to deeper levels of remission.
Molecular measures of disease may augment current endpoints including the potential for …

translating STRIDE‐II into clinical reality–opportunities and challenges

A Dignass, S Rath, T Kleindienst… - Alimentary …, 2023 - Wiley Online Library
Background With the introduction of novel therapies for inflammatory bowel diseases
(IBD),'treat‐to‐target'strategies are increasingly discussed to improve short‐and long‐term …

Early diagnosis, early stratification, and early intervention to deliver precision medicine in IBD

NM Noor, P Sousa, S Paul… - Inflammatory Bowel …, 2022 - academic.oup.com
Despite huge advances in understanding the molecular basis of IBD, clinical management
has continued to rely on a “trial and error” approach. In addition, a therapeutic ceiling has …