Steroid-free deep remission at one year does not prevent Crohn's disease progression: long-term data from the TAILORIX trial
D Laharie, G D'Haens, M Nachury, G Lambrecht… - Clinical …, 2022 - Elsevier
Background & Aims Crohn's disease (CD) patients included in the Tailored Treatment With
Infliximab for Active Crohn's Disease (TAILORIX) trial started infliximab in combination with …
Infliximab for Active Crohn's Disease (TAILORIX) trial started infliximab in combination with …
Iron deficiency anemia impacts disease progression and healthcare resource consumption in patients with inflammatory bowel disease: a real-world evidence study
G Fiorino, JF Colombel, K Katsanos… - Therapeutic …, 2023 - journals.sagepub.com
Background: Iron deficiency anemia (IDA) is a common extraintestinal manifestation of
inflammatory bowel disease (IBD), affecting around one-third of patients. Objective: To …
inflammatory bowel disease (IBD), affecting around one-third of patients. Objective: To …
[HTML][HTML] Moving towards more patient-centred clinical trials in IBD
Moving towards more patient-centred clinical trials in IBD | Nature Reviews Gastroenterology
& Hepatology Skip to main content Thank you for visiting nature.com. You are using a browser …
& Hepatology Skip to main content Thank you for visiting nature.com. You are using a browser …
Higher fiber intake is associated with reduced risk of related surgery among individuals with inflammatory bowel disease in a prospective cohort study
M Deng, L Dan, S Ye, X Chen, X Wang, L Tian… - The Journal of …, 2023 - Elsevier
Background Evidence for the effects of dietary fiber on adverse outcomes in individuals with
inflammatory bowel disease (IBD) is insufficient and controversial. Objectives We aimed to …
inflammatory bowel disease (IBD) is insufficient and controversial. Objectives We aimed to …
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?
Inflammatory bowel disease (IBD) is an emerging global disease characterised by chronic
inflammation of the gastrointestinal tract. However, IBD is also manifested by several …
inflammation of the gastrointestinal tract. However, IBD is also manifested by several …
Is prevention the best way to modify inflammatory bowel disease? How close are we?
J Torres, RC Ungaro, JF Colombel - Gastroenterology, 2022 - Elsevier
Despite improved therapeutic strategies and expanding therapeutic targets, inflammatory
bowel disease remains a disabling disease with potential to progress and lead to …
bowel disease remains a disabling disease with potential to progress and lead to …
[HTML][HTML] Upadacitinib achieves clinical and endoscopic outcomes in Crohn's disease regardless of prior biologic exposure
L Peyrin-Biroulet, R Panaccione, E Louis… - Clinical …, 2024 - Elsevier
ABSTRACT BACKGROUND & AIMS Upadacitinib, an oral Janus kinase inhibitor, achieved
significantly higher rates of clinical remission and endoscopic response vs placebo during …
significantly higher rates of clinical remission and endoscopic response vs placebo during …
[HTML][HTML] Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response
W Yang, Y Wang, T Wang, C Li, L Shi, P Zhang, Y Yin… - Genes & …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic relapsing gastrointestinal disorder, while the
treatment effect is not satisfactory. Immune responsive gene 1 (IRG1) is a highly expressed …
treatment effect is not satisfactory. Immune responsive gene 1 (IRG1) is a highly expressed …
[HTML][HTML] Pharmacological Therapy in Inflammatory Bowel Diseases: A Narrative Review of the Past 90 Years
Inflammatory Bowel Diseases had their first peak in incidence in countries in North America,
Europe, and Oceania and are currently experiencing a new acceleration in incidence …
Europe, and Oceania and are currently experiencing a new acceleration in incidence …
Induction and maintenance treatment with upadacitinib improves health-related quality of life in patients with moderately to severely active ulcerative colitis: phase 3 …
J Panés, EV Loftus Jr, PDR Higgins… - Inflammatory bowel …, 2023 - academic.oup.com
Background We evaluated the health-related quality of life (HRQoL) benefits of upadacitinib
(UPA) induction and maintenance treatment in a phase 3 study of patients with ulcerative …
(UPA) induction and maintenance treatment in a phase 3 study of patients with ulcerative …