In the past two decades, major breakthroughs that improve our understanding of the
pathophysiology and therapy of kidney stones (KS) have been lacking. The disease …

Nephrolithiasis is an increasingly prevalent condition, especially in high income countries,
and is associated with high morbidity. Extraordinary progress in genetics made the …

Calcium oxalate (CaOx) stones are the most prevalent type of kidney stones. CaOx crystals
can stimulate reactive oxygen species (ROS) generation and induce renal oxidative stress to …

Kidney stones are a common form of nephrolithiasis, affecting up to 15% of the world's
population with a high probability of recurrence. These stones exhibit various chemical …

Purpose Changes in dietary protein intake metabolically affect kidney functions. However,
knowledge on potential adverse consequences of long-term higher protein intake (HPI) for …

Kidney stone, one of the oldest known diseases, has plagued humans for centuries,
consistently imposing a heavy burden on patients and healthcare systems worldwide due to …

Background Cystinuria is a rare genetic kidney stone disease, with no cure. Current
treatments involve lowering urinary cystine levels and increasing cystine solubility. This …

The role of diet in the pathogenesis of uric acid (UA) nephrolithiasis is incompletely
understood. This study investigated the effect of dietary intervention on the risk of UA stone …

This study examined the profile of patients and the impact of diet on the risk of brushite stone
formation under controlled, standardized conditions. Sixty-five patients with brushite …

Objective Prevalence of kidney stone disease continues to increase globally with recurrence
rates between 30% and 50% despite technological and scientific advances. Reduction in …