[HTML][HTML] Efficacy and safety of intratracheal IFN-γ treatment to reverse stroke-induced susceptibility to pulmonary bacterial infections

S Jagdmann, D Berchtold, B Gutbier… - Journal of …, 2021 - Elsevier
Stroke-induced immunosuppression contributes to the development of stroke-associated
pneumonia (SAP). Experiments in mice demonstrated that apoptosis of IFN-γ producing …

[PDF][PDF] 胆碱能抗炎通路对脓毒症调控机制的研究进展

刘清香, 谢剑锋, 杨毅, 江苏 - 中华危重病急救医学, 2019 - cccm-em120.com
过强或持续的炎症反应是脓毒症的重要病理生理特征, 其造成的组织损伤和器官功能障碍与患者
预后相关. 胆碱能抗炎通路通过迷走神经释放乙酰胆碱(ACh) 作用于炎性细胞表面α7 …

Differential expression of cholinergic system components in human induced pluripotent stem cells, bone marrow-derived multipotent stromal cells, and induced …

R Weist, T Flörkemeier, Y Roger, S Noack… - Stem Cells and …, 2018 - liebertpub.com
The components of the cholinergic system are evolutionary very old and conserved
molecules that are expressed in typical spatiotemporal patterns. They are involved in …

The protective effect of α7‐nACh receptor and its interaction with 5‐HT1B/1D receptors in acute intestinal ischemia‐reperfusion injury in rats

F Gharishvandi, H Shafaroodi… - Fundamental & …, 2022 - Wiley Online Library
Over the past decades, great attention has been given to the nervous system modulating
effects on the immune response in inflammation‐associated injuries, such as acute intestinal …

[HTML][HTML] Medicinal nicotine in COVID-19 acute respiratory distress syndrome, the new corticosteroid

F Ahmad - World Journal of Critical Care Medicine, 2022 - ncbi.nlm.nih.gov
The cholinergic anti-inflammatory pathway (CAP) refers to the anti-inflammatory effects
mediated by the parasympathetic nervous system. Existence of this pathway was first …

[HTML][HTML] Mode of photoexcited C60 fullerene involvement in potentiating cisplatin toxicity against drug-resistant L1210 cells

D Franskevych, S Prylutska, I Grynyuk, G Pasichnyk… - BioImpacts …, 2019 - ncbi.nlm.nih.gov
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Introduction: C 60 fullerene has received great attention as a candidate for biomedical …

Molecular modelling studies on ɑ7 nicotinic receptor allosteric modulators yields novel filter-based virtual screening protocol

S Al Rawashdah, A Hamrouni, B Sadek, R Amer… - Journal of Molecular …, 2019 - Elsevier
The ɑ7 receptor is a member in the nicotinic acetylcholine receptor (nAChR) which has
been implicated in several neurological disorders. Beside normal agonists and antagonists …

Study of the transcutaneous auricular vagus nerve stimulation may advance outcome in chronic pediatric inflammatory diseases

U Andersson - Medical Research Archives, 2022 - esmed.org
The recent insight that the immune system is innervated has initiated a search for neural
reflex circuits suitable for therapeutic targeting in human inflammatory diseases. The …

Neuroprotective effect of emodin on acute brain injury in sepsis mice

D Yan, LIU Gang, L ZHANG… - Jie Fang Jun Yi Xue Za …, 2019 - search.proquest.com
Objective To investigate the neuroprotective effect and corresponding mechanism of emodin
on acute brain injury in sepsis mice. Methods Male BALB/c mice were randomly divided into …

[HTML][HTML] α7nAChR 基因敲除HIV-1gp120 转基因小鼠模型的构建

胡彤彤, 龚泽龙, 万宇, 李煜彬, 高雪锋… - Journal of Southern …, 2020 - ncbi.nlm.nih.gov
α7nAChR基因敲除HIV-1gp120转基因小鼠模型的构建- PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …