The advent of tyrosine kinase inhibitors (TKI) into the management of patients with chronic
myeloid leukemia (CML) has profoundly improved prognosis. Survival of responders is …

Abstract The Philadelphia (Ph) chromosome, resulting from the t (9; 22)(q34; q11)
translocation, can be found in chronic myeloid leukemia (CML) as well as in a subset of …

Chronic myeloid leukemia (CML) is defined by the presence of Philadelphia chromosome
(Ph) which results from a reciprocal translocation between chromosomes 9 and 22 [t (9; 22] …

Long-Term Follow-Up of the French Stop Imatinib (STIM1) Study in Patients With Chronic
Myeloid Leukemia Page 1 JOURNAL OF CLINICAL ONCOLOGY ORIGINAL REPORT Long-Term …

Chronic myeloid leukemia (CML) is defined by the presence of Philadelphia chromosome
(Ph), resulting from a reciprocal translocation between chromosomes 9 and 22 [t (9; 22] that …

Abstract STOP second generation (2G)–tyrosine kinase inhibitor (TKI) is a multicenter
observational study designed to evaluate 2G-TKI discontinuation in chronic myeloid …

Background First-line imatinib treatment can be successfully discontinued in patients with
chronic myeloid leukaemia after deep molecular response has been sustained for at least 2 …

Abstract Treatment-free remission (TFR) in patients with chronic myeloid leukemia in chronic
phase (CML-CP) is considered a feasible option, especially with the ability of second …

Purpose ENESTfreedom is evaluating treatment-free remission (TFR) following frontline
nilotinib in patients with chronic myeloid leukemia (CML) in chronic phase. Following our …

Tyrosine kinase inhibitors (TKIs) have vastly improved long-term outcomes for patients with
chronic myeloid leukemia (CML). After imatinib (a first-generation TKI), second-and third …