Cancer-related fatigue—mechanisms, risk factors, and treatments

JE Bower - Nature reviews Clinical oncology, 2014 - nature.com
Fatigue is one of the most common adverse effects of cancer that might persist for years after
treatment completion in otherwise healthy survivors. Cancer-related fatigue causes …

Cancer treatment and survivorship statistics, 2012

R Siegel, C DeSantis, K Virgo, K Stein… - CA: a cancer journal …, 2012 - Wiley Online Library
Although there has been considerable progress in reducing cancer incidence in the United
States, the number of cancer survivors continues to increase due to the aging and growth of …

What does plasma CRP tell us about peripheral and central inflammation in depression?

JC Felger, E Haroon, TA Patel, DR Goldsmith… - Molecular …, 2020 - nature.com
Peripheral blood C-reactive protein (CRP) is a biomarker used clinically to measure
systemic inflammation and is reproducibly increased in a subset of patients with major …

Cancer-related fatigue, version 2.2015

AM Berger, K Mooney, A Alvarez-Perez… - Journal of the National …, 2015 - jnccn.org
Cancer-related fatigue is defined as a distressing, persistent, subjective sense of physical,
emotional, and/or cognitive tiredness or exhaustion related to cancer or cancer treatment …

Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications

JC Felger, FE Lotrich - Neuroscience, 2013 - Elsevier
Mounting evidence indicates that inflammatory cytokines contribute to the development of
depression in both medically ill and medically healthy individuals. Cytokines are important …

A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers

CL Raison, RE Rutherford, BJ Woolwine… - JAMA …, 2013 - jamanetwork.com
Context Increased concentrations of inflammatory biomarkers predict antidepressant
nonresponse, and inflammatory cytokines can sabotage and circumvent the mechanisms of …

The role of cytokines in breast cancer development and progression

M Esquivel-Velázquez, P Ostoa-Saloma… - Journal of Interferon & …, 2015 - liebertpub.com
Cytokines are highly inducible, secretory proteins that mediate intercellular communication
in the immune system. They are grouped into several protein families that are referred to as …

Inflammation effects on motivation and motor activity: role of dopamine

JC Felger, MT Treadway - Neuropsychopharmacology, 2017 - nature.com
Motivational and motor deficits are common in patients with depression and other psychiatric
disorders, and are related to symptoms of anhedonia and motor retardation. These deficits in …

Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior

E Haroon, CL Raison, AH Miller - Neuropsychopharmacology, 2012 - nature.com
The potential contribution of chronic inflammation to the development of neuropsychiatric
disorders such as major depression has received increasing attention. Elevated biomarkers …

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

M Maes, M Berk, L Goehler, C Song, G Anderson… - BMC medicine, 2012 - Springer
It is of considerable translational importance whether depression is a form or a consequence
of sickness behavior. Sickness behavior is a behavioral complex induced by infections and …