[HTML][HTML] An update on the role of Hippo signaling pathway in ischemia-associated central nervous system diseases

X Wei, G Huang, J Liu, J Ge, W Zhang, Z Mei - Biomedicine & …, 2023 - Elsevier
The most frequent reason of morbidity and mortality in the world, cerebral ischemia sets off a
chain of molecular and cellular pathologies that associated with some central nervous …

Epilepsy and epileptiform activity in late-onset Alzheimer disease: Clinical and pathophysiological advances, gaps and conundrums

A Kamondi, M Grigg-Damberger, W Löscher… - Nature Reviews …, 2024 - nature.com
A growing body of evidence has demonstrated a link between Alzheimer disease (AD) and
epilepsy. Late-onset epilepsy and epileptiform activity can precede cognitive deterioration in …

[HTML][HTML] Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain

S Sirko, C Schichor, P Della Vecchia, F Metzger… - Nature Medicine, 2023 - nature.com
The glial environment influences neurological disease progression, yet much of our
knowledge still relies on preclinical animal studies, especially regarding astrocyte …

[HTML][HTML] MicroRNAs as potential biomarkers of post-traumatic epileptogenesis: a systematic review

AA Vasilieva, EE Timechko, KD Lysova… - International Journal of …, 2023 - mdpi.com
Structural or post-traumatic epilepsy often develops after brain tissue damage caused by
traumatic brain injury, stroke, infectious diseases of the brain, etc. Most often, between the …

The role of NPY signaling pathway in diagnosis, prognosis and treatment of stroke

T Jiang, T Zheng, R Li, J Sun, X Luan, M Wang - Neuropeptides, 2024 - Elsevier
Neuropeptide Y (NPY), an extensively distributed neurotransmitter within the central nervous
system (CNS), was initially detected and isolated from the brain of a pig in 1982. By binding …

The Association of Epileptic Seizures after Acute Ischemic Stroke with Cerebral Cortical Involvement and Electroencephalographic Changes

A Šmigelskytė, G Rimkuvienė, D Žukaitė, G Repečkaitė… - Medicina, 2024 - mdpi.com
Background and objectives: while acute ischemic stroke is the leading cause of epilepsy in
the elderly population, data about its risk factors have been conflicting. Therefore, the aim of …

GPR56: A potential therapeutic target for neurological and psychiatric disorders

W Qi, W Guan - Biochemical Pharmacology, 2024 - Elsevier
GPR56, also known as GPR56/ADGRG1, is a member of the ADGRG subgroup belonging to
adhesion G protein-coupled receptors (aGPCRs). aGPCRs are the second largest subfamily …

Inhibition of Neuron-Restrictive Silencing Factor (REST/NRSF) Chromatin Binding Attenuates Epileptogenesis

AM Hall, N Kamei, M Shao, HS Mun, K Chen, Y Chen… - Eneuro, 2024 - eneuro.org
The mechanisms by which brain insults lead to subsequent epilepsy remain unclear. Insults
including trauma, stroke, infections, and long seizures (status epilepticus, SE) increase the …

Clinical approaches for poststroke seizure: a review

HU Ryu, HJ Kim, BS Shin, HG Kang - Frontiers in Neurology, 2024 - frontiersin.org
Poststroke seizure is a potential complication of stroke, which is the most frequent acute
symptomatic seizure in adults. Patients with stroke may present with an abnormal or …

Ironing out the Links: Ferroptosis in epilepsy and SUDEP

F Moscovicz, C Taborda, F Fernández, N Borda… - Epilepsy & Behavior, 2024 - Elsevier
Iron is a crucial element for almost all organisms because it plays a vital role in oxygen
transport, enzymatic processes, and energy generation due to its electron transfer …