Exosomes regulate the epithelial–mesenchymal transition in cancer
J Jiang, J Li, X Zhou, X Zhao, B Huang, Y Qin - Frontiers in Oncology, 2022 - frontiersin.org
Exosomes are important mediators of intercellular communication and participate in
complex biological processes by transferring a variety of bioactive molecules between cells …
complex biological processes by transferring a variety of bioactive molecules between cells …
A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cells
Epithelial-mesenchymal heterogeneity implies that cells within the same tumor can exhibit
different phenotypes—epithelial, mesenchymal, or one or more hybrid epithelial …
different phenotypes—epithelial, mesenchymal, or one or more hybrid epithelial …
Functional annotation of ESR1 gene fusions in estrogen receptor-positive breast cancer
RNA sequencing (RNA-seq) detects estrogen receptor alpha gene (ESR1) fusion transcripts
in estrogen receptor-positive (ER+) breast cancer, but their role in disease pathogenesis …
in estrogen receptor-positive (ER+) breast cancer, but their role in disease pathogenesis …
miR-665 expression predicts poor survival and promotes tumor metastasis by targeting NR4A3 in breast cancer
XG Zhao, JY Hu, J Tang, W Yi, MY Zhang, R Deng… - Cell death & …, 2019 - nature.com
Cancer metastasis is the main cause of death in breast cancer (BC) patients. Therefore,
prediction and treatment of metastasis is critical for enhancing the survival of BC patients. In …
prediction and treatment of metastasis is critical for enhancing the survival of BC patients. In …
Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT
CE Aban, A Lombardi, G Neiman, MC Biani… - Scientific reports, 2021 - nature.com
Epithelial to mesenchymal transition (EMT) is a critical cellular process that has been well
characterized during embryonic development and cancer metastasis and it also is …
characterized during embryonic development and cancer metastasis and it also is …
FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E‐cadherin and CD44 expression
Y Hong, H Qin, Y Li, Y Zhang, X Zhuang… - Journal of cellular …, 2019 - Wiley Online Library
Circular RNAs (circRNAs) are a new class of RNAs, and many studies have identified
thousands of circRNAs in tumor cells. Fibronectin type III domain‐containing protein 3B …
thousands of circRNAs in tumor cells. Fibronectin type III domain‐containing protein 3B …
Breast cancer dormancy: need for clinically relevant models to address current gaps in knowledge
Breast cancer is the most commonly diagnosed cancer in the USA. Although advances in
treatment over the past several decades have significantly improved the outlook for this …
treatment over the past several decades have significantly improved the outlook for this …
Role of epithelial-mesenchymal transition in tumor progression
NA Gloushankova, IY Zhitnyak, SN Rubtsova - Biochemistry (Moscow), 2018 - Springer
Epithelial–mesenchymal transition (EMT) is a fundamental process of morphogenesis
whereby epithelial cells acquire the mesenchymal phenotype. Multiple data suggest a …
whereby epithelial cells acquire the mesenchymal phenotype. Multiple data suggest a …
Circulating tumor cell-derived preclinical models: current status and future perspectives
Despite the advancements made in the diagnosis and treatment of cancer, the stages
associated with metastasis remain largely incurable and represent the primary cause of …
associated with metastasis remain largely incurable and represent the primary cause of …
The role of circulating biomarkers in lung cancer
Lung cancer is the leading cause of cancer morbidity and mortality worldwide and early
diagnosis is crucial for the management and treatment of this disease. Non-invasive means …
diagnosis is crucial for the management and treatment of this disease. Non-invasive means …