The advantages and challenges of using FDG PET/CT for response assessment in melanoma in the era of targeted agents and immunotherapy
The treatment of melanoma has been revolutionised in recent years by advances in the
understanding of the genomic landscape of this disease, which has led to the development …
understanding of the genomic landscape of this disease, which has led to the development …
The natural course of cutaneous melanoma
U Leiter, F Meier, B Schittek… - Journal of surgical …, 2004 - Wiley Online Library
The natural course of cutaneous melanoma (CM) is determined by its metastatic spread and
depends on tumor thickness, ulceration, gender, localization, and the histologic subtype of …
depends on tumor thickness, ulceration, gender, localization, and the histologic subtype of …
Melanocytic tumors of uncertain malignant potential: results of a tutorial held at the XXIX Symposium of the International Society of Dermatopathology in Graz, October …
L Cerroni, R Barnhill, D Elder, G Gottlieb… - The American journal …, 2010 - journals.lww.com
Several reports demonstrated the difficulties and lack of agreement in the histopathologic
diagnosis of particular melanocytic tumors (atypical Spitz tumors, atypical blue nevi, deep …
diagnosis of particular melanocytic tumors (atypical Spitz tumors, atypical blue nevi, deep …
Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: a meta-analysis of 18 trials involving 2,621 patients
NJ Ives, RL Stowe, P Lorigan… - Journal of clinical oncology, 2007 - ascopubs.org
Purpose To assess the effect of adding interferon-α (IFN)±interleukin-2 (IL-2) to
chemotherapy in patients with metastatic melanoma. Methods A published data meta …
chemotherapy in patients with metastatic melanoma. Methods A published data meta …
Reflectance-mode confocal microscopy of pigmented skin lesions–improvement in melanoma diagnostic specificity
G Pellacani, AM Cesinaro, S Seidenari - Journal of the American Academy …, 2005 - Elsevier
BACKGROUND: In vivo confocal microscopy enables skin visualization with a
quasihistopathologic resolution. OBJECTIVE: We sought to describe confocal features in …
quasihistopathologic resolution. OBJECTIVE: We sought to describe confocal features in …
Curcumin‐induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IκB kinase and nuclear factor κB activity and are …
DR Siwak, S Shishodia, BB Aggarwal, R Kurzrock - Cancer, 2005 - Wiley Online Library
BACKGROUND Nuclear factor‐κB (NF‐κB) plays a central role in cell survival and
proliferation in human melanoma; therefore, the authors explored the possibility of exploiting …
proliferation in human melanoma; therefore, the authors explored the possibility of exploiting …
Diagnostic Performance of Whole Body Dual Modality 18F-FDG PET/CT Imaging for N- and M-Staging of Malignant Melanoma: Experience With 250 Consecutive …
MJ Reinhardt, AY Joe, U Jaeger, A Huber… - Journal of clinical …, 2006 - ascopubs.org
Purpose To assess the diagnostic performance of positron emission tomography/computed
tomography (PET/CT) using 18F-fluorodeoxyglucose (FDG) for N-and M-staging of …
tomography (PET/CT) using 18F-fluorodeoxyglucose (FDG) for N-and M-staging of …
A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin αvβ3, ± dacarbazine in patients with stage IV metastatic melanoma
P Hersey, J Sosman, S O'Day… - … Journal of the …, 2010 - Wiley Online Library
BACKGROUND: The alpha v beta 3 (αvβ3) integrin is involved in intracellular signaling
regulating cell proliferation, migration, and differentiation and is important for tumor‐induced …
regulating cell proliferation, migration, and differentiation and is important for tumor‐induced …
The microanatomic location of metastatic melanoma in sentinel lymph nodes predicts nonsentinel lymph node involvement
DJ Dewar, B Newell, MA Green, AP Topping… - Journal of Clinical …, 2004 - ascopubs.org
Purpose Sentinel node biopsy is now widely accepted as the most accurate prognostic
indicator in melanoma, and is important in guiding management of patients with clinical …
indicator in melanoma, and is important in guiding management of patients with clinical …
[PDF][PDF] The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma
F Meier, B Schittek, S Busch, C Garbe, K Smalley… - Front …, 2005 - article.imrpress.com
Introduction 3. Ras-Raf-MEK-ERK (MAPK) signaling pathway in melanoma 3.1. The Ras-Raf-
MEK-ERK (MAPK) signaling pathway 3.2. Activation of MAPK signaling pathway in …
MEK-ERK (MAPK) signaling pathway 3.2. Activation of MAPK signaling pathway in …