Sepsis occurs when an infection exceeds local tissue containment and induces a series of
dysregulated physiologic responses that result in organ dysfunction. A subset of patients …

Sepsis is a systemic inflammatory response induced by an infection, leading to organ
dysfunction and mortality. Historically, sepsis-induced organ dysfunction and lethality were …

Sepsis, a clinical syndrome occurring in patients following infection or injury, is a leading
cause of morbidity and mortality worldwide. Current immunological mechanisms do not …

The endothelium provides an essential and selective membrane barrier that regulates the
movement of water, solutes, gases, macromolecules and the cellular elements of the blood …

While protective, the acute inflammatory response when uncontrolled can lead to further
tissue damage and chronic inflammation that is now widely recognized to play important …

Histone acetylation regulates activation and repression of multiple inflammatory genes
known to play critical roles in chronic inflammatory diseases. However, proteins responsible …

Sepsis remains the leading cause of death in most intensive care units. Advances in
understanding the immune response to sepsis provide the opportunity to develop more …

The majority of bacteremias do not develop to sepsis: bacteria are cleared from the
bloodstream. Oxygen released from erythrocytes and humoral immunity kill bacteria in the …

A Review of GM-CSF Therapy in Sepsis : Medicine A Review of GM-CSF Therapy in Sepsis :
Medicine Log in or Register Get new issue alertsGet alerts Secondary Logo Journal Logo …

The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by
high levels of virus replication and dissemination, dysregulated immune responses …