Serum paraoxonase-1 activity and risk of incident cardiovascular disease: The PREVEND study and meta-analysis of prospective population studies
SK Kunutsor, SJL Bakker, RW James, RPF Dullaart - Atherosclerosis, 2016 - Elsevier
Abstract Background Paraoxonase-1 (PON-1) has been suggested to be associated with
cardiovascular disease (CVD) risk, however, aspects of the association, such as shape and …
cardiovascular disease (CVD) risk, however, aspects of the association, such as shape and …
Serum paraoxonase-1 activity is more closely related to HDL particle concentration and large HDL particles than to HDL cholesterol in Type 2 diabetic and non …
RPF Dullaart, JD Otvos, RW James - Clinical biochemistry, 2014 - Elsevier
Objectives We determined relationships of the anti-oxidative enzyme, paraoxonase-1 (PON-
1), with high density lipoprotein (HDL) subfractions, and tested whether these relationships …
1), with high density lipoprotein (HDL) subfractions, and tested whether these relationships …
Serum paraoxonase 1 activity is paradoxically maintained in nonalcoholic fatty liver disease despite low HDL cholesterol [S]
EH van den Berg, EG Gruppen, RW James… - Journal of lipid …, 2019 - ASBMB
Nonalcoholic fatty liver disease (NAFLD) is characterized by low HDL cholesterol, but the
activity of the HDL-associated antioxidative enzyme paraoxonase-1 (PON-1) remains …
activity of the HDL-associated antioxidative enzyme paraoxonase-1 (PON-1) remains …
Pon1 deficiency promotes Trem2 pathway–mediated microglial phagocytosis and inhibits pro-inflammatory cytokines release in vitro and in vivo
L Zhang, W Dong, Y Ma, L Bai, X Zhang, C Sun… - Molecular …, 2022 - Springer
Abstract Paraoxonase 1 (PON1) plays an anti-inflammatory role in the cardiovascular
system. Levels of serum PON1 and polymorphisms in this gene were linked to Alzheimer's …
system. Levels of serum PON1 and polymorphisms in this gene were linked to Alzheimer's …
High sensitive C-reactive protein and serum amyloid A are inversely related to serum bilirubin: effect-modification by metabolic syndrome
PE Deetman, SJL Bakker, RPF Dullaart - Cardiovascular Diabetology, 2013 - Springer
Background Bilirubin has been implicated in cardiovascular protection by virtue of its anti-
inflammatory and anti-oxidative properties. The metabolic syndrome is featured by …
inflammatory and anti-oxidative properties. The metabolic syndrome is featured by …
Plasma ApoE elevations are associated with NAFLD: the PREVEND study
EH van den Berg, JP Corsetti, SJL Bakker… - PLoS …, 2019 - journals.plos.org
Non-alcoholic fatty liver disease (NAFLD) is featured by increased plasma very low density
lipoproteins (VLDL). The extent to which plasma apolipoprotein E (ApoE) levels are elevated …
lipoproteins (VLDL). The extent to which plasma apolipoprotein E (ApoE) levels are elevated …
Low serum paraoxonase-1 activity associates with incident cardiovascular disease risk in subjects with concurrently high levels of high-density lipoprotein cholesterol …
JP Corsetti, CE Sparks, RW James, SJL Bakker… - Journal of clinical …, 2019 - mdpi.com
Paroxonase-1 (PON1) is a key enzyme that inhibits low-density lipoprotein oxidation and
consequently atherogenesis. Here, we assessed whether low serum PON1 activity …
consequently atherogenesis. Here, we assessed whether low serum PON1 activity …
Increased large VLDL and small LDL particles are related to lower bilirubin in Type 2 diabetes mellitus
RPF Dullaart, R de Vries, JD Lefrandt - Clinical biochemistry, 2014 - Elsevier
Objectives Bilirubin may protect against atherosclerotic cardiovascular disease by virtue of
its anti-oxidative properties, but lower bilirubin may also be associated to atherogenic …
its anti-oxidative properties, but lower bilirubin may also be associated to atherogenic …
[HTML][HTML] Low serum paraoxonase1 activity levels predict coronary artery disease severity
T Sun, J Hu, Z Yin, Z Xu, L Zhang, L Fan, Y Zhuo… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Paraoxonase1 (PON1) activity is closely related to coronary artery disease (CAD).
However, whether PON1 activity can predict the degree of coronary stenosis remains …
However, whether PON1 activity can predict the degree of coronary stenosis remains …
The inverse association of HDL-cholesterol with future risk of hypertension is not modified by its antioxidant constituent, paraoxonase-1: The PREVEND prospective …
Background and aims High-density lipoprotein cholesterol (HDL-C), an established risk
marker for atherosclerotic cardiovascular disease (CVD), has been shown to be inversely …
marker for atherosclerotic cardiovascular disease (CVD), has been shown to be inversely …