The renin-angiotensin-aldosterone system and the kidney: effects on kidney disease
UC Brewster, MA Perazella - The American journal of medicine, 2004 - Elsevier
The renin-angiotensin-aldosterone system regulates renal vasomotor activity, maintains
optimal salt and water homeostasis, and controls tissue growth in the kidney. However …
optimal salt and water homeostasis, and controls tissue growth in the kidney. However …
ACE2 and ACE: structure-based insights into mechanism, regulation and receptor recognition by SARS-CoV
L Lubbe, GE Cozier, D Oosthuizen, KR Acharya… - Clinical …, 2020 - portlandpress.com
Angiotensin converting enzyme (ACE) is well-known for its role in blood pressure regulation
via the renin–angiotensin aldosterone system (RAAS) but also functions in fertility, immunity …
via the renin–angiotensin aldosterone system (RAAS) but also functions in fertility, immunity …
Serial triggering of many T-cell receptors by a few peptide–MHC complexes
S Valitutti, S Müller, M Cella, E Padovan… - Nature, 1995 - nature.com
T LYMPHOCYTES can recognize and be activated by a very small number of complexes of
peptide with major histocompatibility complex (MHC) molecules displayed on the surface of …
peptide with major histocompatibility complex (MHC) molecules displayed on the surface of …
Male–female differences in fertility and blood pressure in ACE-deficient mice
Abstract ANGIOTENSIN-CONVERTING enzyme (ACE) is a dipeptidyl carboxy-peptidase that
generates the vasoconstricting peptide angiotensin II and inactivates the vasodilating …
generates the vasoconstricting peptide angiotensin II and inactivates the vasodilating …
Paracrine regulation of the renal microcirculation
There has been an explosive growth of interest in the multiple interacting paracrine systems
that influence renal microvascular function. This review first discusses the membrane …
that influence renal microvascular function. This review first discusses the membrane …
Angiotensin II and the fibroproliferative response to acute lung injury
RP Marshall, P Gohlke, RC Chambers… - … of Physiology-Lung …, 2004 - journals.physiology.org
Angiotensin II (ANG II), generated by activation of local renin-angiotensin systems, is
believed to play an important role in tissue repair and remodeling, in part via transforming …
believed to play an important role in tissue repair and remodeling, in part via transforming …
Targeting drug delivery in the vascular system: Focus on endothelium
PM Glassman, JW Myerson, LT Ferguson… - Advanced drug delivery …, 2020 - Elsevier
The bloodstream is the main transporting pathway for drug delivery systems (DDS) from the
site of administration to the intended site of action. In many cases, components of the …
site of administration to the intended site of action. In many cases, components of the …
Regulation of intrarenal angiotensin II in hypertension
LG Navar, LM Harrison-Bernard, A Nishiyama… - …, 2002 - Am Heart Assoc
Intrarenal angiotensin II (Ang II) is regulated by several complex processes involving
formation from both systemically delivered and intrarenally formed substrate, as well as …
formation from both systemically delivered and intrarenally formed substrate, as well as …
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
SM Keyse, EA Emslie - Nature, 1992 - nature.com
REACTIVE oxygen species have been implicated both in the ageing process and in
degenerative diseases, including arthritis and cancer1, 2. Bacteria adapt to the lethal effects …
degenerative diseases, including arthritis and cancer1, 2. Bacteria adapt to the lethal effects …
Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide
KB Brosnihan, P Li, CM Ferrario - Hypertension, 1996 - Am Heart Assoc
Abstract Angiotensin-(1-7)[Ang-(1-7)] was recently recognized to have novel biological
functions that are distinct from those of Ang II. In these studies, we determined the vasoactive …
functions that are distinct from those of Ang II. In these studies, we determined the vasoactive …