Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association

SD De Ferranti, J Steinberger, R Ameduri, A Baker… - Circulation, 2019 - Am Heart Assoc
This scientific statement presents considerations for clinical management regarding the
assessment and risk reduction of select pediatric populations at high risk for premature …

Oxidative stress in ulcerative colitis: an old concept but a new concern

G Jena, PP Trivedi, B Sandala - Free radical research, 2012 - Taylor & Francis
Ulcerative colitis is an idiopathic, chronic and relapsing inflammatory bowel disease, which
elicits the risk of colorectal cancer, the third most common malignancy in humans. It has …

MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis

G Koukos, C Polytarchou, JL Kaplan… - Gastroenterology, 2013 - Elsevier
Background & Aims Altered levels and functions of microRNAs (miRs) have been associated
with inflammatory bowel diseases (IBDs), although little is known about their roles in …

Rising incidence of inflammatory bowel disease among children: a 12-year study

HM Malaty, X Fan, AR Opekun… - Journal of pediatric …, 2010 - journals.lww.com
Objective: Data suggest an increase in the incidence of pediatric inflammatory bowel
disease (IBD). We examined the trend of the incidence of IBD in children. Patients and …

Increased expression of Toll-like receptor (TLR) 2 and TLR4 in the colonic mucosa of children with inflammatory bowel disease

B Szebeni, G Veres, A Dezsofi, K Rusai… - Clinical & …, 2008 - academic.oup.com
Inflammatory bowel disease (IBD) may result from exaggerated stimulation of the mucosal
immune system by luminal bacterial flora. Bacterial products are recognized by pattern …

Surgical management of Crohn disease in children: guidelines from the Paediatric IBD Porto Group of ESPGHAN

J Amil-Dias, S Kolacek, D Turner… - Journal of pediatric …, 2017 - journals.lww.com
The incidence of Crohn disease (CD) has been increasing and surgery needs to be
contemplated in a substantial number of cases. The relevant advent of biological treatment …

Highlights in IBD epidemiology and its natural history in the paediatric age

M Gasparetto, G Guariso - Gastroenterology research and …, 2013 - Wiley Online Library
Background. The number of patients of all age brackets diagnosed with Inflammatory Bowel
Disease (IBD) has risen dramatically worldwide over the past 50 years. IBD's changing …

LC–MS/MS for protein and peptide quantification in clinical chemistry

M Rauh - Journal of Chromatography B, 2012 - Elsevier
The LC-triple quadrupole mass spectrometer (LC–MS/MS) is an increasingly common tool in
the clinical laboratory. Established applications include routine assays for detecting inborn …

The requirements and barriers to successful transition of adolescents with inflammatory bowel disease: differing perceptions from a survey of adult and paediatric …

S Sebastian, H Jenkins, S McCartney… - Journal of Crohn's …, 2012 - academic.oup.com
Background and aim: Preliminary data highlight the importance of appropriate transition for
successful transfer of adolescents with IBD from paediatric to adult care. The aim of this …

Early life stress enhances the vulnerability to chronic psychosocial stress and experimental colitis in adult mice

AH Veenema, SO Reber, S Selch, F Obermeier… - …, 2008 - academic.oup.com
Early life stress enhances the vulnerability to both mood and chronic inflammatory disorders,
suggesting a link between these stress-related disorders. To study this, we exposed male …