The emergence of multidrug resistance (MDR) in malignant tumors is one of the leading
threats encountered currently in many chemotherapeutic agents. The overexpression of the …

Covering: 2013 to 2021 As the characteristic metabolites of Euphorbia plants, Euphorbia
diterpenoids have always been a hot topic in related science communities due to their …

Ethnopharmacological relevance Euphorbia is one of the major genera in angiosperms,
which is widely distributed all over the world, including Asia, Africa and Central and South …

Two novel diterpenoids, one with a rearranged trans, trans-fused tricyclo [10.3. 0.04, 6]
pentadecane framework (1) and the other with an unprecedented 15 S configuration (2) …

Euphorbia stracheyi Boiss was used for hemostasis, analgesia, and muscular regeneration
in traditional Chinese medicine. To study the chemical constituents of E. stracheyi, the ethyl …

Thirteen undescribed diterpenoids, including an ent-isopimarane (1), ten ent-atisanes (2–8
and 15–17), and two ingenanes (20 and 21) and ten known compounds, were separated …

Phytochemical investigation into the medium polar fraction of the ethanol extract of
Euphorbia peplus led to the identification of 32 diterpenoids with five structural types …

The development of collateral sensitivity agents that are able to modulate P-glycoprotein (P-
gp) is the most promising approaches to overcome multidrug resistance (MDR) in cancer. In …

Phytochemical investigation of the whole plant of Euphorbia peplus Linn. led to the isolation
of previously uncharacterized jatrophane type diterpenoid euphopepluanone L (1), along …

Three undescribed jatrophane diterpenoids, named euphpepluones PR (1–3), were isolated
from the whole plant Euphorbia peplus. The structures of these compounds were elucidated …