Mechanisms underlying neurodegenerative disorders and potential neuroprotective activity of agrifood by-products

C Angeloni, M Malaguti, C Prata, M Freschi… - Antioxidants, 2022 - mdpi.com
Neurodegenerative diseases, characterized by progressive loss in selected areas of the
nervous system, are becoming increasingly prevalent worldwide due to an aging population …

Magnolol attenuates depressive-like behaviors by polarizing microglia towards the M2 phenotype through the regulation of Nrf2/HO-1/NLRP3 signaling pathway

W Tao, Y Hu, Z Chen, Y Dai, Y Hu, M Qi - Phytomedicine, 2021 - Elsevier
Purpose Magnolol (MA) exhibits anti-depressant effect by inhibiting inflammation. However,
its effect on microglia polarization remains not fully understood. Herein, our study was …

Sulfide and transition metals-A partnership for life

BK Maiti, LB Maia, JJG Moura - Journal of Inorganic Biochemistry, 2022 - Elsevier
Sulfide and transition metals often came together in Biology. The variety of possible
structural combinations enabled living organisms to evolve an array of highly versatile metal …

Potential Antioxidative and Anti-Hyperuricemic Components Targeting Superoxide Dismutase and Xanthine Oxidase Explored from Polygonatum Sibiricum Red.

J Li, Z Wang, M Fan, G Hu, M Guo - Antioxidants, 2022 - mdpi.com
Polygonatum sibiricum Red.(P. sibiricum) has been used as a traditional Chinese medicine
with a wide range of pharmacology effects. However, the responsible bioactive compounds …

New Lignanamides with Antioxidant and Anti-Inflammatory Activities Screened Out and Identified from Warburgia ugandensis Combining Affinity Ultrafiltration LC-MS …

XC Zhuang, GL Chen, Y Liu, YL Zhang, MQ Guo - Antioxidants, 2021 - mdpi.com
Warburgia ugandensis, also known as “green heart,” is widely used for the treatment of
various diseases as a traditional ethnomedicinal plant in local communities in Africa. In this …

Ethnopharmacology, phytochemistry and biological activities of native chilean plants

B Salehi, J Sharifi-Rad, J Herrera-Bravo… - Current …, 2021 - ingentaconnect.com
The native flora of Chile has unique characteristics due to the geographical situation of the
country, with the vast desert in the North, Patagonia in the South, the Andean Mountains on …

Combating Parkinson's disease with plant-derived polyphenols: Targeting oxidative stress and neuroinflammation

RM Gahtani, S Shoaib, U Hani, R Jayachithra… - Neurochemistry …, 2024 - Elsevier
Parkinson's disease (PD) is a devastating neurodegenerative disorder predominantly
affecting the elderly, characterized by the loss of dopaminergic neurons in the substantia …

[HTML][HTML] Antioxidant and anti-Alzheimer activities of Clivia miniata (Lindl) roots, bulbs, and aerial parts: In-vitro and in-silico studies

AS ElNagar, MM Mohyeldin, NM Mostafa… - Biomedicine & …, 2023 - Elsevier
Clivia miniata (Lindl) is a member of the family Amaryllidaceae known for its chemically
diverse alkaloids with a wide range of biological activities. Many reports revealed a direct …

[HTML][HTML] Magnolol against enterovirus 71 by targeting Nrf2-SLC7A11-GSH pathway

D Zhao, X Guo, B Lin, R Huang, H Li, Q Wang… - Biomedicine & …, 2024 - Elsevier
Abstract Enterovirus 71 (EV71), a prominent pathogen associated with hand, foot, and
mouth disease (HFMD), has been reported worldwide. To date, the advancement of effective …

Metabolites of Procyanidins From Litchi Chinensis Pericarp With Xanthine Oxidase Inhibitory Effect and Antioxidant Activity

Y Sui, J Shi, S Cai, T Xiong, B Xie, Z Sun, X Mei - Frontiers in Nutrition, 2021 - frontiersin.org
Procyanidins from litchi pericarp (LPPC) has been evidenced to possess strong antioxidant
activities in vivo that is possibly correlated with their intestinal metabolites. However, the …