Complex regulatory effects of gut microbial short-chain fatty acids on immune tolerance and autoimmunity
CH Kim - Cellular & molecular immunology, 2023 - nature.com
Immune tolerance deletes or suppresses autoreactive lymphocytes and is established at
multiple levels during the development, activation and effector phases of T and B cells …
multiple levels during the development, activation and effector phases of T and B cells …
The role of inflammation in autoimmune disease: a therapeutic target
Y Xiang, M Zhang, D Jiang, Q Su, J Shi - Frontiers in Immunology, 2023 - frontiersin.org
Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …
increasing year by year. AIDs are produced by the immune system's misidentification of self …
T follicular helper cells in autoimmune diseases
X Wei, X Niu - Journal of Autoimmunity, 2023 - Elsevier
T follicular helper (Tfh) cells with the phenotype of mainly expressing surface molecules
CXC motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting …
CXC motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting …
Immune‐related adverse events after immune check point inhibitors: Understanding the intersection with autoimmunity
N Singh, AM Hocking, JH Buckner - Immunological Reviews, 2023 - Wiley Online Library
Immune checkpoint inhibitor therapies act through blockade of inhibitory molecules involved
in the regulation of T cells, thus releasing tumor specific T cells to destroy their tumor targets …
in the regulation of T cells, thus releasing tumor specific T cells to destroy their tumor targets …
Endocrine-disrupting chemicals and autoimmune diseases
RG Huang, XB Li, YY Wang, H Wu, KD Li, X Jin… - Environmental …, 2023 - Elsevier
Endocrine-disrupting chemicals (EDCs) widely exist in people's production and life which
have great potential to damage human and animal health. Over the past few decades …
have great potential to damage human and animal health. Over the past few decades …
Inhibition of glutaminolysis ameliorates lupus by regulating T and B cell subsets and downregulating the mTOR/P70S6K/4EBP1 and NLRP3/caspase-1/IL-1β …
X Zhang, G Wang, Y Bi, Z Jiang, X Wang - International …, 2022 - Elsevier
Background and Aim of the Study Systemic lupus erythematosus (SLE) is an autoimmune
disease characterized by lymphocyte imbalance. The differentiation and function of T and B …
disease characterized by lymphocyte imbalance. The differentiation and function of T and B …
B cell metabolism in autoimmune diseases: signaling pathways and interventions
Autoimmune diseases are heterogeneous disorders believed to stem from the immune
system's inability to distinguish between auto-and foreign-antigens. B lymphocytes serve a …
system's inability to distinguish between auto-and foreign-antigens. B lymphocytes serve a …
Immunosensors for autoimmune-disease-related biomarkers: A literature review
CE Karachaliou, E Livaniou - Sensors, 2023 - mdpi.com
Immunosensors are a special class of biosensors that employ specific antibodies for
biorecognition of the target analyte. Immunosensors that target disease biomarkers may be …
biorecognition of the target analyte. Immunosensors that target disease biomarkers may be …
Microplastics exposure induced and exacerbated the development of systemic lupus erythematosus in mice
H Chen, L Wan, Y Qiu, F Qiu, C Wen, Y Mao… - Science of The Total …, 2024 - Elsevier
Environmental exposure may function as a contributing risk factor in the development of
systemic lupus erythematosus (SLE). Recently, the global issue of microplastics (MPs) …
systemic lupus erythematosus (SLE). Recently, the global issue of microplastics (MPs) …
Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity
A Bodansky, JL David, A Rallistan, M Kalaycioglu… - The Journal of Clinical …, 2024 - jci.org
Given the global surge in autoimmune diseases, it is critical to evaluate emerging
therapeutic interventions. Despite numerous new targeted immunomodulatory therapies …
therapeutic interventions. Despite numerous new targeted immunomodulatory therapies …