Objectives To study the mechanism by which the readthrough mutation in TNFRSF11B,
encoding osteoprotegerin (OPG) with additional 19 amino acids at its C-terminus (OPG-XL) …

Aging remains a primary risk factor for a host of diseases, including leading causes of death.
Aging and associated diseases are inherently multifactorial, with numerous contributing …

Photoaging is an important extrinsic aging factor leading to altered skin morphology and
reduced function. Prior work has revealed a connection between photoaging and loss of …

Although several studies assess the biological effects of micro and titanium dioxide
nanoparticles (TiO2 NPs), the literature shows controversial results regarding their effect on …

Introduction: Engineered 3D models employing human induced pluripotent stem cell
(hiPSC) derivatives have the potential to recapitulate the cell diversity and structure found in …

3D cell culture models have gained popularity in recent years as an alternative to animal
and 2D cell culture models for pharmaceutical testing and disease modeling …

The lack of appropriate experimental models often limits our ability to investigate the
establishment of infections in specific tissues. To reproduce the structural and spatial …

Developing in vitro models that accurately mimic the microenvironment of biological
structures or processes holds substantial promise for gaining insights into specific biological …

Heat inactivation of bovine sera is routinely performed in cell culture laboratories.
Nevertheless, it remains debatable whether it is still necessary due to the improvement of …

The use of 3D cell cultures has gained increasing importance in medical and
pharmaceutical research. However, the analysis of the culture medium is hardly …