Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Inflammatory markers in dysmenorrhea and therapeutic options

Z Barcikowska, E Rajkowska-Labon… - International journal of …, 2020 - mdpi.com
Dysmenorrhea often significantly reduces the quality of women's life and is still an important
public health problem. Despite numerous studies, the pathomechanism of dysmenorrhea is …

[HTML][HTML] Understanding the impact of uterine fibroids on human endometrium function

A Navarro, MV Bariani, Q Yang… - Frontiers in cell and …, 2021 - frontiersin.org
Uterine fibroids (leiomyomas) are the most common benign gynecological tumors in women
of reproductive age worldwide. They cause heavy menstrual bleeding, usually leading to …

Role of inflammation in benign gynecologic disorders: from pathogenesis to novel therapies

A AlAshqar, L Reschke, GW Kirschen… - Biology of …, 2021 - academic.oup.com
Emerging evidence supports the notion that inflammation fosters the development of
common benign gynecologic disorders, including uterine leiomyoma, endometriosis, and …

Pro-angiogenic activity and vasculogenic mimicry in the tumor microenvironment by leptin in cancer

AK Herrera-Vargas, E Garcia-Rodriguez… - Cytokine & growth factor …, 2021 - Elsevier
The acquired ability to induce the formation of a functional vasculature is a hallmark of
cancer. Blood vessels in tumors are formed through various mechanisms, among the most …

Association between obesity and the risk of uterine fibroids: a systematic review and meta-analysis

H Qin, Z Lin, E Vásquez, X Luan, F Guo… - J Epidemiol Community …, 2021 - jech.bmj.com
Background Uterine fibroids (UFs) are the most common form of sex steroid hormone-
dependent benign tumours that grow in the walls of the uterus. Several observational …

Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
Uterine fibroids (UFs) are the most important benign neoplastic threat to women's health
worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy …

Vascular biology of uterine fibroids: connecting fibroids and vascular disorders

GW Kirschen, A AlAshqar, M Miyashita-Ishiwata… - …, 2021 - rep.bioscientifica.com
Fibroids are benign tumors caused by the proliferation of myometrial smooth muscle cells in
the uterus that can lead to symptoms such as abdominal pain, constipation, urinary …

Shark new antigen receptor (IgNAR): structure, characteristics and potential biomedical applications

SN Juma, X Gong, S Hu, Z Lv, J Shao, L Liu, G Chen - Cells, 2021 - mdpi.com
Shark is a cartilaginous fish that produces new antigen receptor (IgNAR) antibodies. This
antibody is identified with a similar human heavy chain but dissimilar sequences. The …

Cytokine-polymorphisms associated with Preeclampsia: A review

C Mora-Palazuelos, M Bermúdez, M Aguilar-Medina… - Medicine, 2022 - journals.lww.com
Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of
pregnancies and is diagnosed principally when hypertension appears in the second-d half …