Malaria: progress, perils, and prospects for eradication
There are still approximately 500 million cases of malaria and 1 million deaths from malaria
each year. Yet recently, malaria incidence has been dramatically reduced in some parts of …
each year. Yet recently, malaria incidence has been dramatically reduced in some parts of …
Malaria in pregnancy: pathogenesis and immunity
Understanding of the biological basis for susceptibility to malaria in pregnancy was recently
advanced by the discovery that erythrocytes infected with Plasmodium falciparum …
advanced by the discovery that erythrocytes infected with Plasmodium falciparum …
Plasmodium falciparum Erythrocyte Membrane Protein 1 Diversity in Seven Genomes – Divide and Conquer
TS Rask, DA Hansen, TG Theander… - PLoS computational …, 2010 - journals.plos.org
The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …
Antigenic Variation in Plasmodium falciparum
The persistence of the human malaria parasite Plasmodium falciparum during blood stage
proliferation in its host depends on the successive expression of variant molecules at the …
proliferation in its host depends on the successive expression of variant molecules at the …
PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study
SB Sirima, L Richert, A Chêne, AT Konate… - The Lancet Infectious …, 2020 - thelancet.com
Background PRIMVAC is a VAR2CSA-derived placental malaria vaccine candidate aiming
to prevent serious clinical outcomes of Plasmodium falciparum infection during pregnancy …
to prevent serious clinical outcomes of Plasmodium falciparum infection during pregnancy …
Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
MD Larsen, M Lopez-Perez, EK Dickson… - Nature …, 2021 - nature.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
5′ flanking region of var genes nucleate histone modification patterns linked to phenotypic inheritance of virulence traits in malaria parasites
JJ Lopez‐Rubio, AM Gontijo, MC Nunes… - Molecular …, 2007 - Wiley Online Library
In the human malaria parasite Plasmodium falciparum antigenic variation facilitates long‐
term chronic infection of the host. This is achieved by sequential expression of a single …
term chronic infection of the host. This is achieved by sequential expression of a single …
[HTML][HTML] Malaria in pregnancy: linking immunity and pathogenesis to prevention
SJ Rogerson, V Mwapasa… - Defining and Defeating …, 2007 - ncbi.nlm.nih.gov
Pregnant women are susceptible to malaria during pregnancy. Plasmodium falciparum,
which sequesters in the placenta, causes the greatest disease, contributing significantly to …
which sequesters in the placenta, causes the greatest disease, contributing significantly to …
Antigenic Variation in Plasmodium falciparum: Gene Organization and Regulation of the var Multigene Family
SA Kyes, SM Kraemer, JD Smith - Eukaryotic cell, 2007 - Am Soc Microbiol
Plasmodium falciparum imposes an enormous burden upon the developing world, with 300
to 500 million cases and 1 to 2 million deaths per year (94). Despite extensive research …
to 500 million cases and 1 to 2 million deaths per year (94). Despite extensive research …