Background—Infective endocarditis is a potentially lethal disease that has undergone major
changes in both host and pathogen. The epidemiology of infective endocarditis has become …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Infective endocarditis (IE), initially described more than 350 years ago, involves infection of
the endocardial surface of the heart. The clinical manifestations of IE can involve every …

Background The timing and indications for surgical intervention to prevent systemic
embolism in infective endocarditis remain controversial. We conducted a trial to compare …

Background—The purpose of this study was to assess the incidence of neurological
complications in patients with infective endocarditis, the risk factors for their development …

The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

Background Antithrombotic therapy in valvular disease is important to mitigate
thromboembolism, but the hemorrhagic risk imposed must be considered. Methods The …

Abstract purpose: This study was designed to develop improved criteria for the diagnosis of
infective endocarditis and to compare these criteria with currently accepted criteria in a large …

Echocardiography plays a key role in the assessment of infective endocarditis (IE). It is
useful for the diagnosis of endocarditis, the assessment of the severity of the disease, the …

This chapter about antithrombotic therapy for valvular heart disease is part of the American
College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) …