Oestrogens and their receptors contribute broadly to physiology and diseases. In
premenopausal women, endogenous oestrogens protect against cardiovascular, metabolic …

The G Protein-Coupled Estrogen Receptor (GPER) is a novel membrane-bound receptor
that mediates non-genomic actions of the primary female sex hormone 17β-estradiol …

Estrogen receptors (ER) mediate functions beyond their endocrine roles, as modulation of
cardiovascular, renal, and immune systems through anti-inflammatory and anti-apoptotic …

17β-Estradiol (E2) is the main estrogenic hormone in the body and exerts many
cardiovascular protective effects. Via three receptors known to date, including estrogen …

Amyloid-β (Aβ) is one of the causes of Alzheimer's disease (AD), damaging nerve
membranes and inducing neurotoxicity. AD is more prevalent in female patients than in male …

Cav1. 2 plays an essential role in learning and memory, drug addiction, and neuronal
development. Intracellular calcium homeostasis is disrupted in neurodegenerative diseases …

Voltage-gated calcium channels (VGCCs) and estrogen receptors are important cellular
proteins that have been shown to interact with each other across varied cells and tissues …

Acute myocardial infarction (MI) is associated with an intense inflammatory response that is
critical for cardiac repair but is also involved in the pathogenesis of adverse cardiac …

G protein-coupled receptor 30 (GPR30), also named G protein-coupled estrogen receptor
(GPER), and the β 1-adrenergic receptor (β1AR) are G protein-coupled receptors (GPCR) …

Aging-related diseases, especially vascular and neurological disorders cause huge
economic burden. How to delay vascular and neurological aging is one of the …