Heart failure is a common, costly, and debilitating syndrome that is associated with a highly
complex drug regimen, a large number of comorbidities, and a large and often disparate …

Perioperative cardiovascular complications are important causes of morbidity and mortality
associated with non-cardiac surgery, particularly in patients with coronary artery disease …

Focused ultrasound (FUS) in combination with systemically injected microbubbles can be
used to non-invasively open the blood-brain barrier (BBB) in targeted regions for a variety of …

Intravital microscopy is increasingly used to visualize and quantitate dynamic biological
processes at the (sub) cellular level in live animals. By visualizing tissues through imaging …

For more than 100 yr, scientists have studied the sympathetic nervous system and its
cardiovascular control mechanisms. Muscle sympathetic activity is the most important direct …

Invasive cardiac output (CO) monitoring, traditionally performed with transpulmonary
thermodilution techniques, is usually reserved for high-risk patients because of the inherent …

January 2017• Volume 124• Number 1 www. anesthesia-analgesia. org 63 maintenance of
an optimal gas exchange. 3–6 The principal use of pulse oximetry in mechanically ventilated …

To determine whether a classification based on the contour of the photoplethysmography
signal (PPGc) can detect changes in systolic arterial blood pressure (SAP) and vascular …

Background Studies have shown that permissive hypotension for uncontrolled hemorrhagic
shock can result in good resuscitation outcome. The ideal target mean arterial pressure …

General anesthetics cause hemodynamic instability and alter blood flow to various organs.
There is mounting evidence that most general anesthetics, at clinical concentrations …