Abstract Purpose Angiotensin II (Ang II)-induced vascular contraction is mediated by Ca 2+-
dependent mechanisms and Ca 2+ sensitization mechanisms. The phosphorylation of …

Anesthesia is frequently used to facilitate physiological monitoring during interventional
animal studies. However, its use may induce cardiovascular (central and peripheral) …

Dexmedetomidine, a highly selective α-2 adrenoceptor agonist, produces vasoconstriction,
which leads to transiently increased blood pressure. The goal of this study was to investigate …

The goals of this study were to examine the cellular signaling pathways associated with the
phosphorylation of caldesmon, the phosphorylation-dependent inhibitory protein of myosin …

Background Epinephrine (EPI) or norepinephrine (NOR) is widely used to treat
cardiovascular collapse during lipid emulsion (LE) resuscitation for drug toxicity. However …

Background Hemorrhagic shock is associated with changes in vascular responsiveness that
may lead to organ dysfunction and, ultimately, multiple organ dysfunction syndrome. Volatile …

This study examined the possible upstream cellular signaling pathway associated with nitric
oxide (NO)-mediated inhibition of phenylephrine-induced contraction in isolated rat aortae in …

Laboratory mice (Mus musculus) are susceptible to hypothermia, especially during
anesthetic events, disease states, and exposure to environmental stressors. Thermal …

Introduction. Patients with severe aortic stenosis (AS) undergoing surgery are at increased
risk of hypotension and hypoperfusion. Although treatable with inotropic agents or fluid, little …

Background: This review evaluates the possible cardiac side effects of general anesthetic
agents upon usage. Cardiac as well as non-cardiac surgery may precipitate adverse events …