Other than natriuretic peptides, neurohumoral markers have not been studied adequately in
heart failure with preserved systolic function. There is little evidence of chronic activation of …

We compared the activity and physiologic effects of cardiac angiotensin converting enzyme
(ACE) using isovolumic hearts from male Wistar rats with left ventricular hypertrophy due to …

The heart responds in well-defined ways to abnormal loads that are placed on it. The result
of this response, cardiac hypertrophy, has been extensively studied in the last decade, and …

Left ventricular muscle mass is increased in the presence of large body size, high blood
pressure and obesity, but the relative contributions to ventricular mass of these and other …

The weak relation of systolic blood pressure to left ventricular mass in hypertensive patients
is often interpreted as evidence of nonhemodynamic stimuli to muscle growth. To test the …

Background Antihypertensive drugs may differ in their ability to reduce LV mass. Covariates
other than drug selection, such as pretreatment LV mass, body weight, the magnitude of …

OBJECTIVE: Cardiac growth may be modulated in part by the trophic effects of
neurohormones. The aim of the present study was to investigate the relation between the …

In order to compare variability in M-mode echography and MRI in the assessment of left
ventricular mass, 20 echogenic patients without evidence of coronary artery disease were …

Conflicting results have been reported for the roles of cGMP and cGMP-dependent protein
kinase I (cGKI) in various pathological conditions leading to cardiac hypertrophy and …

BACKGROUND Cardiac hypertrophy is associated with elevated intracardiac angiotensin-
converting enzyme activity, which may contribute to diastolic dysfunction. METHODS AND …