[HTML][HTML] Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies
L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
[HTML][HTML] Breast cancer metastasis: mechanisms and therapeutic implications
Breast cancer is the most common malignancy in women worldwide. Metastasis is the
leading cause of high mortality in most cancers. Although predicting the early stage of breast …
leading cause of high mortality in most cancers. Although predicting the early stage of breast …
[HTML][HTML] Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions
In the past decades, transcriptomic studies have revolutionized cancer treatment and
diagnosis. However, tumor sequencing strategies typically result in loss of spatial …
diagnosis. However, tumor sequencing strategies typically result in loss of spatial …
Liposomes and extracellular vesicles as drug delivery systems: A comparison of composition, pharmacokinetics, and functionalization
L van der Koog, TB Gandek… - Advanced healthcare …, 2022 - Wiley Online Library
Over the past decades, lipid‐based nanoparticle drug delivery systems (DDS) have caught
the attention of researchers worldwide, encouraging the field to rapidly develop improved …
the attention of researchers worldwide, encouraging the field to rapidly develop improved …
[HTML][HTML] Breast cancer treatments: updates and new challenges
A Burguin, C Diorio, F Durocher - Journal of personalized medicine, 2021 - mdpi.com
Breast cancer (BC) is the most frequent cancer diagnosed in women worldwide. This
heterogeneous disease can be classified into four molecular subtypes (luminal A, luminal B …
heterogeneous disease can be classified into four molecular subtypes (luminal A, luminal B …
[HTML][HTML] Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins
K Pance, JA Gramespacher, JR Byrnes… - Nature …, 2023 - nature.com
Targeted degradation of cell surface and extracellular proteins via lysosomal delivery is an
important means to modulate extracellular biology. However, these approaches have …
important means to modulate extracellular biology. However, these approaches have …
A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells
E Seung, Z Xing, L Wu, E Rao, V Cortez-Retamozo… - Nature, 2022 - nature.com
Effective antitumour immunity depends on the orchestration of potent T cell responses
against malignancies. Regression of human cancers has been induced by immune …
against malignancies. Regression of human cancers has been induced by immune …
[HTML][HTML] Subtypes of breast cancer
E Orrantia-Borunda, P Anchondo-Nuñez… - Breast Cancer …, 2022 - ncbi.nlm.nih.gov
Breast cancer is a genetically and clinically heterogeneous disease with multiple subtypes.
The classification of these subtypes has evolved over the years. The most common and …
The classification of these subtypes has evolved over the years. The most common and …
[HTML][HTML] Current state of breast cancer diagnosis, treatment, and theranostics
A Bhushan, A Gonsalves, JU Menon - Pharmaceutics, 2021 - mdpi.com
Breast cancer is one of the leading causes of cancer-related morbidity and mortality in
women worldwide. Early diagnosis and effective treatment of all types of cancers are crucial …
women worldwide. Early diagnosis and effective treatment of all types of cancers are crucial …
Delivery of CRISPR/Cas systems for cancer gene therapy and immunotherapy
The clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-
associated protein (Cas) systems are efficient and versatile gene editing tools, which offer …
associated protein (Cas) systems are efficient and versatile gene editing tools, which offer …