The role of the autonomic nervous system in the pathophysiology of obesity

D Guarino, M Nannipieri, G Iervasi, S Taddei… - Frontiers in …, 2017 - frontiersin.org
Obesity is reaching epidemic proportions globally and represents a major cause of
comorbidities, mostly related to cardiovascular disease. The autonomic nervous system …

Glucagon-like peptide 1 receptor agonists and heart failure: the need for further evidence generation and practice guidelines optimization

MS Khan, GC Fonarow, DK McGuire, AF Hernandez… - Circulation, 2020 - Am Heart Assoc
With worsening epidemiological trends for both the incidence and prevalence of type 2
diabetes mellitus (T2DM) and heart failure (HF) worldwide, it is critical to implement optimal …

Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose co‐transporter‐2 inhibitors for people with cardiovascular disease: a …

Y Takaoka, T Suzuki, D Yoneoka… - Cochrane Database …, 2021 - cochranelibrary.com
Background Cardiovascular disease (CVD) is a leading cause of death globally. Recently,
dipeptidyl peptidase‐4 inhibitors (DPP4i), glucagon‐like peptide‐1 receptor agonists (GLP …

[HTML][HTML] Determinants of body weight regulation in humans

M Moehlecke, LH Canani, MRM Trindade… - … of endocrinology and …, 2016 - SciELO Brasil
Body weight is regulated by the ability of hypothalamic neurons to orchestrate behavioral,
endocrine and autonomic responses via afferent and efferent pathways to the brainstem and …

Dipeptidyl peptidase-4 inhibition prevents vascular aging in mice under chronic stress: Modulation of oxidative stress and inflammation

M Xin, X Jin, X Cui, C Jin, L Piao, Y Wan, S Xu… - Chemico-biological …, 2019 - Elsevier
Background and aims Chronic psychosocial stress is a risk factor for cardiovascular disease.
In view of the important role of dipeptidyl peptidase-4 (DPP-4) in human pathophysiology …

Diabetic peripheral neuropathy associated with cardiovascular risk factors and glucagon-like peptide-1 concentrations among newly diagnosed patients with type 2 …

T Dinh Le, N Phi Thi Nguyen… - … and Obesity: Targets …, 2022 - Taylor & Francis
Purpose This study was aimed at the prevalence, cardiovascular risk factors of diabetic
peripheral neuropathy (DPN), and the relationship between DPN and fasting glucagon-like …

Exenatide acutely increases heart rate in parallel with augmented sympathetic nervous system activation in healthy overweight males

MM Smits, MHA Muskiet, L Tonneijck… - British Journal of …, 2016 - Wiley Online Library
Aim Clinical use of glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) is consistently
associated with heart rate (HR) acceleration in type 2 diabetes patients. We explored the …

The emerging role of metformin in gestational diabetes mellitus

SG Gray, TM McGuire, N Cohen… - Diabetes, Obesity and …, 2017 - Wiley Online Library
Metformin use during pregnancy is controversial and there is disparity in the acceptance of
metformin treatment in women with gestational diabetes mellitus (GDM) in Australia. Despite …

Gastrointestinal physiology

MO Welcome - Cham: Springer International Publishing.[Google …, 2018 - Springer
The digestive system is responsible for about 60–90% of diseases that affect humans,
making the digestive system one of the most important systems in life processes. This book …

Vildagliptin stimulates endothelial cell network formation and ischemia-induced revascularization via an endothelial nitric-oxide synthase-dependent mechanism

M Ishii, R Shibata, K Kondo, T Kambara… - Journal of Biological …, 2014 - ASBMB
Dipeptidyl peptidase-4 inhibitors are known to lower glucose levels and are also beneficial
in the management of cardiovascular disease. Here, we investigated whether a dipeptidyl …