Recent advances in the design and discovery of synthetic tyrosinase inhibitors
J Li, L Feng, L Liu, F Wang, L Ouyang, L Zhang… - European Journal of …, 2021 - Elsevier
Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …
A systematic review of synthetic tyrosinase inhibitors and their structure-activity relationship
Z Peng, G Wang, QH Zeng, Y Li, H Liu… - Critical Reviews in …, 2022 - Taylor & Francis
Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …
Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4H)-Oxazolone-Based Sulfonamides
Since the synthesis of prontosil the first prodrug shares their chemical moiety, sulfonamides
exhibit diverse modes of actions to serve as antimicrobials, diuretics, antidiabetics, and other …
exhibit diverse modes of actions to serve as antimicrobials, diuretics, antidiabetics, and other …
Synthesis, computational molecular docking analysis and effectiveness on tyrosinase inhibition of kojic acid derivatives
Tyrosinase inhibitors have become increasingly important as whitening agents and for the
treatment of pigmentary disorders. In this study, the synthesis of kojic acid derivatives having …
treatment of pigmentary disorders. In this study, the synthesis of kojic acid derivatives having …
A novel water soluble axially substituted silicon (IV) phthalocyanine bearing quaternized 4-(4-pyridinyl) phenol groups: Synthesis, characterization …
SY Al-Raqa, K Khezami, EN Kaya, M Durmuş - Polyhedron, 2021 - Elsevier
Abstract The novel axially bis [4-(4-pyridinyl) phenol] substituted silicon (IV) phthalocyanine
(3) and its quaternized derivative (3Q) were designed and synthesized. These …
(3) and its quaternized derivative (3Q) were designed and synthesized. These …
Novel water soluble morpholine substituted Zn (II) phthalocyanine: Synthesis, characterization, DNA/BSA binding, DNA photocleavage and topoisomerase I inhibition
In this study, novel peripherally tetra 3-morpholinophenol substituted zinc (II) phthalocyanine
(4) and its water soluble form quaternized zinc (II) phthalocyanine (ZnQ) were synthesized …
(4) and its water soluble form quaternized zinc (II) phthalocyanine (ZnQ) were synthesized …
[HTML][HTML] Novel oxazolones incorporated azo dye: Design, synthesis photophysical-DFT aspects and antimicrobial assessments with In-silico and In-vitro surveys
FF Albelwi, M Al-Anazi, A Naqvi, ZM Hritani… - … of Photochemistry and …, 2021 - Elsevier
New derivatives of the oxazolone compounds 4 (aj) and (7a-e) containing azo dye moieties
have been prepared via the Erlenmeyer reaction of their azo dye precursors. The …
have been prepared via the Erlenmeyer reaction of their azo dye precursors. The …
The water soluble peripherally tetra-substituted zinc (II), manganese (III) and copper (II) phthalocyanines as new potential anticancer agents
In this study,[2-(2-morpholin-4-ylethoxy) ethoxy] group substituted zinc (II), manganese (III)
and copper (II) phthalocyanines 2–4 and their water soluble derivatives 2a, 3a and 4a were …
and copper (II) phthalocyanines 2–4 and their water soluble derivatives 2a, 3a and 4a were …
Flow chemistry: towards a more sustainable heterocyclic synthesis
Flow Chemistry is a revolutionary field in Organic Chemistry. By changing the conventional
methods and apparatus applied in the chemical synthesis, flow chemistry emerges as a …
methods and apparatus applied in the chemical synthesis, flow chemistry emerges as a …
Synthesis and characterization of metallophthalocyanine with morpholine containing Schiff base and determination of their antimicrobial and antioxidant activities
In this work, novel metallophthalocyanine compounds (M= Zn, Cu, Co) bearing four 2-
methoxy-4-{(Z)-[(4-morpholin-4-ylphenyl) imino] methyl} phenol at the peripheral positions …
methoxy-4-{(Z)-[(4-morpholin-4-ylphenyl) imino] methyl} phenol at the peripheral positions …