Uric acid and oxidative stress—relationship with cardiovascular, metabolic, and renal impairment

ME Gherghina, I Peride, M Tiglis, TP Neagu… - International Journal of …, 2022 - mdpi.com
Background: The connection between uric acid (UA) and renal impairment is well known
due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging …

The pathogenesis of end-stage renal disease from the standpoint of the theory of general pathological processes of inflammation

E Gusev, L Solomatina, Y Zhuravleva… - International journal of …, 2021 - mdpi.com
Chronic kidney disease can progress to end-stage chronic renal disease (ESRD), which
requires the use of replacement therapy (dialysis or kidney transplant) in life-threatening …

The diuretic effects of SGLT2 inhibitors: A comprehensive review of their specificities and their role in renal protection

P Delanaye, AJ Scheen - Diabetes & metabolism, 2021 - Elsevier
Sodium-glucose cotransporter type 2 inhibitors (SGLT2is) are new oral glucose-lowering
agents that provide cardiovascular and renal protection in both patients with and without …

Hypouricemic effect of gallic acid, a bioactive compound from Sonneratia apetala leaves and branches, on hyperuricemic mice

L Jiang, Y Wu, C Qu, Y Lin, X Yi, C Gao, J Cai, Z Su… - Food & function, 2022 - pubs.rsc.org
As a tropical medicinal plant, Sonneratia apetala is mainly distributed in the southeast
coastal areas of China. Recently, the hypouricemic effect of Sonneratia apetala leaves and …

The Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the …

YL Wu, JF Chen, LY Jiang, XL Wu, YH Liu… - Frontiers in …, 2021 - frontiersin.org
Sonneratia apetala Buch-Ham., an exotic mangrove species with antidiabetic, antibacterial,
and antioxidant capacities, mainly distributes in the southeast coastal areas in China. The …

The biomarkers discovery of hyperuricemia and gout: proteomics and metabolomics

X Wu, C You - PeerJ, 2023 - peerj.com
Background Hyperuricemia and gout are a group of disorders of purine metabolism. In
recent years, the incidence of hyperuricemia and gout has been increasing, which is a …

Pharmacological basis for use of a novel compound in hyperuricemia: anti-hyperuricemic and anti-inflammatory effects

L Zhao, Y Li, D Yao, R Sun, S Liu, X Chen… - Frontiers in …, 2021 - frontiersin.org
Background: The prevalence of hyperuricemia is considered high worldwide. Hyperuricemia
occurs due to decreased excretion of uric acid, increased synthesis of uric acid, or a …

Association of uric acid and uric acid to creatinine ratio with chronic kidney disease in hypertensive patients

NR Silva, CET Gonçalves, DLN Gonçalves, RMM Cotta… - BMC nephrology, 2021 - Springer
Background Recent studies have shown that the serum uric acid/creatinine ratio (SUA/SCr)
is a better predictor of chronic kidney disease (CKD) than serum uric acid (SUA) isolated …

Study from the United States: increased prevalence of kidney stones in patients with high weight-adjusted waist index

Z Gui, L Yu, Y Chen, M Zhang, J He, Y Hao - Frontiers in Nutrition, 2024 - frontiersin.org
Objective Using data from NHANES 2007–2018, to examine the association between WWI
(weight-adjusted waist index) index and prevalence of kidney stones. Methods Using …

Nanoparticle-antibody conjugate-based immunoassays for detection of CKD-associated biomarkers

M Chhillar, P Kukkar, KH Kim - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
To date, immunoassays are utilized as a prominent analytical tool for many common
diseases like chronic kidney disease (CKD) not only in early-stage diagnosis but also for …