The folate receptor (FR) is a recognised biomarker for tumour cells due to its overexpression
on a large number of tumours. Consequently, the FR has been exploited by many diagnostic …

Most cancer drugs are designed to interfere with one or more events in cell proliferation or
survival. As healthy cells may also need to proliferate and avoid apoptosis, anticancer …

Abstract Changes in the human gastrointestinal microbiome are associated with several
diseases. To infer causality, experiments in representative models are essential, but widely …

Neural stem and progenitor cells have a central role in the development and evolution of the
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …

Responses of cells to mechanical properties of the adhesion substrate were examined by
culturing normal rat kidney epithelial and 3T3 fibroblastic cells on a collagen-coated …

Caco-2 cells develop morphologic characteristics of normal enterocytes when grown on
plastic dishes or nitrocellulose filters. The purpose of this study was to determine whether …

Epithelium is the tissue phenotype of early embryos and primitive adults of the chordate
phylum. A second tissue type, however, is produced by epithelial-mesenchymal …

We show that a protein with a glycosylphosphatidyl inositol (GPI) anchor can be recovered
from lysates of epithelial cells in a low density, detergent-insoluble form. Under these …

Prediction of chemical-induced hepatotoxicity in humans from in vitro data continues to be a
significant challenge for the pharmaceutical and chemical industries. Generally …

A set of 11 clones encoding putative GTP binding proteins highly homqlogous to the yeast
YP7Y/SEC4 gene products have been isolated from an MDCK cell cDNA library. We …