Quantitative proteomic analysis of histone modifications

H Huang, S Lin, BA Garcia, Y Zhao - Chemical reviews, 2015 - ACS Publications
Several mechanisms have been proposed for histone marks to exert their functions,
including altering the physical properties of nucleosomes by neutralization of charge via …

Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium

K Salnikow, A Zhitkovich - Chemical research in toxicology, 2008 - ACS Publications
Chronic exposure to nickel (II), chromium (VI), or inorganic arsenic (iAs) has long been
known to increase cancer incidence among affected individuals. Recent epidemiological …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Nickel impact on human health: An intrinsic disorder perspective

B Zambelli, VN Uversky, S Ciurli - … et Biophysica Acta (BBA)-Proteins and …, 2016 - Elsevier
The interplay of the presence of nickel and protein disorder in processes affecting human
health is the focus of the present review. Many systems involving nickel as either a cofactor …

Epigenetics in metal carcinogenesis: nickel, arsenic, chromium and cadmium

A Arita, M Costa - Metallomics, 2009 - academic.oup.com
Although carcinogenic metals have been known to disrupt a wide range of cellular
processes the precise mechanism by which they exert their carcinogenic effects is not …

Environmental epigenetics in metal exposure

R Martinez-Zamudio, HC Ha - Epigenetics, 2011 - Taylor & Francis
Although it is widely accepted that chronic exposure to arsenite, nickel, chromium and
cadmium increases cancer incidence in individuals, the molecular mechanisms underlying …

Head and neck cancer due to heavy metal exposure via tobacco smoking and professional exposure: a review

R Khlifi, A Hamza-Chaffai - Toxicology and applied pharmacology, 2010 - Elsevier
Chronic exposures to heavy metals via tobacco smoking and professional exposure may
increase the risk of head and neck cancer, although the epidemiologic evidence is limited by …

Toxicogenomic approaches for understanding molecular mechanisms of heavy metal mutagenicity and carcinogenicity

P Koedrith, HL Kim, JI Weon, YR Seo - International journal of hygiene and …, 2013 - Elsevier
Heavy metals that are harmful to humans include arsenic, cadmium, chromium, lead,
mercury, and nickel. Some metals or their related compounds may even cause cancer …

Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors

Z Herceg - Mutagenesis, 2007 - academic.oup.com
While the field of cancer genetics has enjoyed a great deal of attention among cancer
researchers in the last few decades, the appreciation of cancer epigenetics is more recent …

Elucidating the mechanisms of nickel compound uptake: a review of particulate and nano-nickel endocytosis and toxicity

A Muñoz, M Costa - Toxicology and applied pharmacology, 2012 - Elsevier
Nickel (Ni) is a worldwide pollutant and contaminant that humans are exposed to through
various avenues resulting in multiple toxic responses—most alarming is its clear …