Background: The increased use of heavy metal nickel in modern industries results in
increased environmental impact. Occupational and environmental exposure to nickel is …

The chronic occupational exposure to contaminants and carcinogens leads to the
development of cancer. Over the past decades, many carcinogens have been found in the …

The purpose of this review is to provide a reader with a brief account of current results and
views in the area of genotoxicity of metal ions, with a special attention to underlying …

Nickel compounds are included among human carcinogens, though the molecular events
related to them are not yet completely known. It has been proposed that the basic element …

Clam, a filter-feeding lamellibranch mollusk, is capable to accumulate high levels of trace
metals and has therefore become a model for investigation the mechanism of heavy metal …

The molecular mechanisms of nickel-induced malignant cell transformation include effects
altering the structure and covalent modifications of core histones. Previously, we found that …

Nickel compounds have been found to be carcinogenic based upon epidemiological, animal
and cell culture studies. Previous studies suggest that epigenetic mechanisms play a role in …

The skin and eyes remain in constant exposure to the surrounding environment and are
subject to accidental, occupational, and biological risks at all times. Normal development …

Nickel (Ni), a heavy metal is prevalent in the atmosphere due to both natural and
anthropogenic activities. Ni is a carcinogen implicated in the development of lung and nasal …

Nickel has the potential to produce a variety of pathologic effects in humans. Since it is
widely used in modern industries, the exposures and associated health problems are …