Bacteria evolve as a result of mutations and acquisition of foreign DNA by recombination
processes. A growing body of evidence suggests that mutation and recombination rates are …

Pseudomonas aeruginosa, a widely distributed opportunistic pathogen, is an important
threat to human health for causing serious infections worldwide. Due to its antibiotic …

Sublines of the major P. aeruginosa reference strain PAO1 are derivatives of the original
PAO1 isolate, which are maintained in laboratories worldwide. These sublines display …

Stalled RNA polymerases (RNAPs) pose an obstacle for the replicating complexes, which
could lead to transcription-replication conflicts and result in genetic instability. Stalled …

Nucleoid-associated proteins (NAPs) such as IHF, HU, Fis, and H-NS alter the topology of
bound DNA and may thereby affect accessibility of DNA to repair and recombination …

Lactococcus lactis is subjected to several stressful conditions during industrial fermentation
including oxidation, heating and cooling, acid, high osmolarity/dehydration and starvation …

Aim: To examine the possible role of nucleotide excision repair (NER) in affecting the
ultimate mutagenic potency of26-and3, 5-dimethylaniline (DMA) and their metaboliteS …

Pathogenic bacteria, including P. aeruginosa, are serious threats for human health with their
antibiotic resistance and virulence factors. Since phenolic acids, secondary metabolites of …

Reactive oxygen species (ROS) are a major cause of spontaneous mutations in aerobic
organisms. Among the ROS, hydroxyl radical attacks DNA to produce many kinds of DNA …

Concurrent bacterial replication and transcription lead to conflicts between the two
machineries. These encounters, which impede replication and destabilize genomes, are …