The changing paradigm of drug-resistant tuberculosis treatment: successes, pitfalls, and future perspectives

N Dookie, SL Ngema, R Perumal… - Clinical Microbiology …, 2022 - Am Soc Microbiol
Drug-resistant tuberculosis (DR-TB) remains a global crisis due to the increasing incidence
of drug-resistant forms of the disease, gaps in detection and prevention, models of care, and …

[HTML][HTML] Recent advances in the treatment of tuberculosis

I Motta, M Boeree, D Chesov, K Dheda… - Clinical Microbiology …, 2023 - Elsevier
Background Tuberculosis (TB) is a global health challenge and one of the leading causes of
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …

[图书][B] WHO consolidated guidelines on tuberculosis. Module 4: treatment-drug-resistant tuberculosis treatment, 2022 update

World Health Organization - 2022 - books.google.com
The WHO Consolidated Guidelines on Tuberculosis (TB), Module 4: Treatment-Drug-
Resistant Tuberculosis Treatment 2022 update informs health care professionals in Member …

[图书][B] WHO operational handbook on tuberculosis: module 4: treatment: drug-resistant tuberculosis treatment

World Health Organization - 2020 - apps.who.int
The World Health Organization (WHO) has produced this WHO operational handbook on
tuberculosis to provide practical advice to complement the latest WHO consolidated …

[HTML][HTML] Genome-wide association studies of global Mycobacterium tuberculosis resistance to 13 antimicrobials in 10,228 genomes identify new resistance …

CRyPTIC Consortium - PLoS biology, 2022 - journals.plos.org
The emergence of drug-resistant tuberculosis is a major global public health concern that
threatens the ability to control the disease. Whole-genome sequencing as a tool to rapidly …

[HTML][HTML] Clinical standards for the dosing and management of TB drugs

JWC Alffenaar, SL Stocker, LD Forsman… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND: Optimal drug dosing is important to ensure adequate response to
treatment, prevent development of drug resistance and reduce drug toxicity. The aim of …

Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement

J Domínguez, MJ Boeree, E Cambau… - The Lancet Infectious …, 2023 - thelancet.com
Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-
based methods being considered the gold standard for drug susceptibility testing, molecular …

[图书][B] WHO operational handbook on tuberculosis. Module 3: diagnosis-rapid diagnostics for tuberculosis detection

World Health Organization - 2024 - books.google.com
The “WHO operational handbook on tuberculosis. Module 3: Diagnosis-Rapid diagnostics
for tuberculosis detection, third edition” is the latest edition replacing the one issued in 2021 …

[HTML][HTML] Correlation of N-acetyltransferase 2 genotype and acetylation status with plasma isoniazid concentration and its metabolic ratio in Ethiopian tuberculosis …

T Sileshi, NF Telele, V Burkley, E Makonnen… - Scientific Reports, 2023 - nature.com
Unfavorable treatment outcomes for tuberculosis (TB) treatment might result from altered
plasma exposure to antitubercular drugs in TB patients. The present study investigated the …

Multidrug-resistant tuberculosis in children and adolescents: current strategies for prevention and treatment

JA Seddon, S Johnson, M Palmer… - Expert Review of …, 2021 - Taylor & Francis
Introduction An estimated 30,000 children develop multidrug-resistant (MDR) tuberculosis
(TB) each year, with only a small proportion diagnosed and treated. This field has historically …