Conspectus Facing increasing demand for precision medicine, materials chemistry systems
for bioanalysis with accurate molecular design, controllable structure, and adjustable …

The surface chemistry, pendent functional entities, and ease in tunability of various materials
play a central role in properly coordinating with enzymes for immobilization purposes. Due …

DNAzyme is emerging for gene therapy. The administration of the in vivo catalytic activity of
DNAzyme has proven important but challenging for clinical applications. Herein, we report a …

Therapeutic DNAzymes have unceasingly intrigued the scientific community owing to their
prosperous gene regulation capability. The efficacy of DNAzymes against many types of …

Nucleic acid nanomaterials with good biocompatibility, biodegradability, and
programmability have important applications in biomedical field. Nucleic acid nanomaterials …

Alzheimer disease (AD) is the leading cause of dementia that affects millions of old people.
Despite significant advances in the understanding of AD pathobiology, no disease modifying …

Current clinical approaches to osteoporosis primarily target osteoclast biology, overlooking
the synergistic role of bone cells, immune cells, cytokines, and inorganic components in …

DNAzyme motors are widely used for the sensitive detection of intracellular miRNAs due to
their excellent signal response. Generally, the addition of exogenous mental ions to …

The excellent molecular recognition, programmable and biocompatible properties make
deoxyribonucleic acid (DNA) a kind of material widely used in biomedical field. DNA …

Despite DNA nanotechnology has spawned a broad variety and taken a giant leap toward
cancer theranostic applications over the last decade, the homogeneous DNA nanostructures …