[HTML][HTML] Self-assembled tetrahedral framework nucleic acid mediates tumor-associated macrophage reprogramming and restores antitumor immunity

H Qian, T Zhou, Y Fu, M Guo, W Yang, D Zhang… - … Therapy-Nucleic Acids, 2022 - cell.com
There is increasing interest in depleting or repolarizing tumor-associated macrophages
(TAMs) to generate a proinflammatory effect. However, TAMs usually display an …

A Smart DNA Nanoassembly Containing Multivalent Aptamers Enables Controlled Delivery of CRISPR/Cas9 for Cancer Immunotherapy

Z Lv, Z Li, S Zou, P Li, N Song, R Zhang… - Advanced Functional …, 2024 - Wiley Online Library
CRISPR/Cas9 system is promising for the reversal of tumor immunosuppression in
immunotherapy, but the controlled delivery of CRISPR/Cas9 remains challenging. Herein …

Enhancing Chymotrypsin Activity and Stability of Capillary Immobilized Enzyme Microreactors Using Zeolitic Imidazolate Frameworks as Encapsulation Materials

S Zhang, Y Gan, H Wang, X Qi, P Su, J Song… - Analytical …, 2024 - ACS Publications
Open-tubular immobilized enzyme microreactors (OT-IMERs) are some of the most widely
used enzyme reaction devices due to the advantages of simple preparation and fast sample …

[HTML][HTML] Recent advances of manganese-based hybrid nanomaterials for cancer precision medicine

X Liu, P Rong - Frontiers in Oncology, 2021 - frontiersin.org
Cancer precision medicine (CPM) could tailor the best treatment for individual cancer
patients, while imaging techniques play important roles in its application. With the …

An autonomous synthetic DNA machine for ultrasensitive detection of Salmonella typhimurium based on bidirectional primers exchange reaction cascades

Q Li, M Zhang, Q Zhang, Z Zhu, Z Guo, J Li, W Xu… - Talanta, 2023 - Elsevier
Statistics show that food poisoning caused by Salmonella typhimurium (S. Typhimurium)
often tops the list of bacterial food poisoning types in countries around the world. However …

[HTML][HTML] Trypsin/Zn3(PO4)2 Hybrid Nanoflowers: Controlled Synthesis and Excellent Performance as an Immobilized Enzyme

Z Wang, P Liu, Z Fang, H Jiang - International Journal of Molecular …, 2022 - mdpi.com
Immobilized enzymes are a significant technological approach to retain enzyme activity and
reduce enzyme catalytic cost. In this work, trypsin-incorporated Zn3 (PO4) 2 hybrid …

Self‐Assembled DNA Composite‐Engineered Mesenchymal Stem Cells for Improved Skin‐Wound Repair

Z Li, Y Wang, H Wang, H Wang, Y Shang, S Wang… - Small, 2024 - Wiley Online Library
The direct use of mesenchymal stem cells (MSCs) as therapeutics for skin injuries is a
promising approach, yet it still faces several obstacles, including limited adhesion, retention …

[HTML][HTML] Polymer–DNA assembled nanoflower for targeted delivery of dolastatin-derived microtubule inhibitors

T Wu, Y Shi, T Yang, P Zhao, Z Yang, B Yang - RSC advances, 2024 - pubs.rsc.org
Dolastatin derivatives possess excellent anticancer activity and have been translated into
clinical trials for cancer therapy. Drug delivery systems enable dolastatin derivatives to break …

Bottlebrush DNA-Primed Rolling Circle Amplification for Sensitive Detection of Biomolecules

X Chen, R Zhang, L Peng, Y Du… - ACS Applied Nano …, 2023 - ACS Publications
Development of nucleic acids containing unnatural moieties has expanded the scope of
genetic materials, and modifications of nucleobases have been extensively explored and …

[HTML][HTML] Recent advances in functional nucleic acid decorated nanomaterials for cancer imaging and therapy

L Wu, R Yuan, T Wen, Y Qin, Y Wang, X Luo… - Biomedicine & …, 2024 - Elsevier
Nanomaterials possess unusual physicochemical properties including unique optical,
magnetic, electronic properties, and large surface-to-volume ratio. However, nanomaterials …