[HTML][HTML] NLRP3 Inflammasome's Activation in Acute and Chronic Brain Diseases—An Update on Pathogenetic Mechanisms and Therapeutic Perspectives with …
A Chiarini, L Gui, C Viviani, U Armato, I Dal Prà - Biomedicines, 2023 - mdpi.com
Increasingly prevalent acute and chronic human brain diseases are scourges for the elderly.
Besides the lack of therapies, these ailments share a neuroinflammation that is …
Besides the lack of therapies, these ailments share a neuroinflammation that is …
Selenium-enriched peptides identified from selenium-enriched soybean protein hydrolysate: Protective effects against heat damage in Caco-2 cells
X Chen, W Liu, J Zhang, H Li, X Liu - Food & Function, 2023 - pubs.rsc.org
Our previous study evaluated the antioxidant and anti-inflammatory activities of selenium-
enriched soybean peptides (SePPs) in vivo. In this study, we purified SePPs via gel filtration …
enriched soybean peptides (SePPs) in vivo. In this study, we purified SePPs via gel filtration …
Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors
L González-Cofrade, JP Green, I Cuadrado… - Bioorganic …, 2023 - Elsevier
Dysregulated inflammasome activity, particularly of the NLRP3 inflammasome, is associated
with the development of several inflammatory diseases. The study of molecules directly …
with the development of several inflammatory diseases. The study of molecules directly …
[HTML][HTML] An in silico investigation on the interactions of curcumin and epigallocatechin-3-gallate with NLRP3 inflammasome complex
AB Jena, UC Dash, AK Duttaroy - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Interleukin-1β (IL-1β) and IL-18 are the underlying factors of the inflammatory
response and are necessary for the host's reaction and pathogen resistance. The NLRP3 …
response and are necessary for the host's reaction and pathogen resistance. The NLRP3 …
Repurposing FDA-approved drugs as NLRP3 inhibitors against inflammatory diseases: machine learning and molecular simulation approaches
Activation of NLRP3 (NOD-like receptor family, pyrin domain-containing protein 3) has been
associated with multiple chronic pathologies, including diabetes, atherosclerosis, and …
associated with multiple chronic pathologies, including diabetes, atherosclerosis, and …