Exosomal circRNA: emerging insights into cancer progression and clinical application potential
F Zhang, J Jiang, H Qian, Y Yan, W Xu - Journal of Hematology & …, 2023 - Springer
Exosomal circRNA serves a novel genetic information molecule, facilitating communication
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …
Engineered extracellular vesicles and their mimetics for cancer immunotherapy
C Liu, Y Wang, L Li, D He, J Chi, Q Li, Y Wu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …
cells that are involved in many physiological and pathological processes as intermediaries …
Exosome-derived circCCAR1 promotes CD8+ T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
Z Hu, G Chen, Y Zhao, H Gao, L Li, Y Yin, J Jiang… - Molecular cancer, 2023 - Springer
Abstract Background Circular RNAs (circRNAs) can be encapsulated into exosomes to
participate in intercellular communication, affecting the malignant progression of a variety of …
participate in intercellular communication, affecting the malignant progression of a variety of …
Comprehensive analysis of scRNA-Seq and bulk RNA-Seq reveals dynamic changes in the tumor immune microenvironment of bladder cancer and establishes a …
Background The prognostic management of bladder cancer (BLCA) remains a great
challenge for clinicians. Recently, bulk RNA-seq sequencing data have been used as a …
challenge for clinicians. Recently, bulk RNA-seq sequencing data have been used as a …
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production
X Yao, H Liu, Z Wang, F Lu, W Chen, Q Feng, Y Miao… - Oncogene, 2023 - nature.com
Circular RNAs (circRNAs) play an important role in regulating the development of human
cancers through diverse biological functions. However, the exact molecular mechanisms …
cancers through diverse biological functions. However, the exact molecular mechanisms …
[HTML][HTML] CircRNAs in tumor immunity and immunotherapy: Perspectives from innate and adaptive immunity
LL Yu, Q Xiao, B Yu, QL Lv, ZQ Liu, JY Yin - Cancer Letters, 2023 - Elsevier
Tumor immunotherapy is a new therapeutic approach that has been evolving in the last
decade and has dramatically changed the treatment options for cancer. Circular RNAs …
decade and has dramatically changed the treatment options for cancer. Circular RNAs …
Recent advances of exosomal circRNAs in cancer and their potential clinical applications
Q Yi, J Yue, Y Liu, H Shi, W Sun, J Feng… - Journal of translational …, 2023 - Springer
Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed,
uninterrupted loop. The expression of circRNA differs among cell types and tissues, and …
uninterrupted loop. The expression of circRNA differs among cell types and tissues, and …
Exosomal circRNAs in cancer: implications for therapy resistance and biomarkers
Z Lin, Y Ji, J Zhou, G Li, Y Wu, W Liu, Z Li, T Liu - Cancer Letters, 2023 - Elsevier
Despite the advances in cancer treatment in recent years, the development of resistance to
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …
[HTML][HTML] The potential role and mechanism of circRNA/miRNA axis in cholesterol synthesis
W Chen, J Xu, Y Wu, B Liang, M Yan… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Cholesterol levels are an initiating risk factor for atherosclerosis. Many genes play a central
role in cholesterol synthesis, including HMGCR, SQLE, HMGCS1, FDFT1, LSS, MVK, PMK …
role in cholesterol synthesis, including HMGCR, SQLE, HMGCS1, FDFT1, LSS, MVK, PMK …
[HTML][HTML] Exosomes derived from immune cells: the new role of tumor immune microenvironment and tumor therapy
S Wang, Y Shi - International journal of nanomedicine, 2022 - ncbi.nlm.nih.gov
Exosomes are small vesicles secreted by living cells, with a typical lipid bilayer structure.
They carry a variety of proteins, lipids, RNA and other important information, play an …
They carry a variety of proteins, lipids, RNA and other important information, play an …