Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput

E Rampler, YE Abiead, H Schoeny, M Rusz… - Analytical …, 2020 - ACS Publications
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

The toxicity of nanoparticles and their interaction with cells: an in vitro metabolomic perspective

M Awashra, P Młynarz - Nanoscale Advances, 2023 - pubs.rsc.org
Nowadays, nanomaterials (NMs) are widely present in daily life due to their significant
benefits, as demonstrated by their application in many fields such as biomedicine …

The cardioprotective effects of the new crystal form of puerarin in isoproterenol-induced myocardial ischemia rats based on metabolomics

Y Zhou, M Li, J Song, Y Shi, X Qin, Z Gao, Y Lv, G Du - Scientific reports, 2020 - nature.com
Puerarin has shown unique pharmacological effects on myocardial ischemia (MI). Changing
the crystal form is an effective approach to improve the cardioprotective effects of puerarin …

Applications of metabolomics in forensic toxicology and forensic medicine

M Szeremeta, K Pietrowska… - International Journal of …, 2021 - mdpi.com
Forensic toxicology and forensic medicine are unique among all other medical fields
because of their essential legal impact, especially in civil and criminal cases. New high …

Seaweed metabolomics: A review on its nutrients, bioactive compounds and changes in climate change

E Park, H Yu, JH Lim, JH Choi, KJ Park, J Lee - Food Research …, 2023 - Elsevier
Seaweed, an important food resource in several Asian countries, contains various
metabolites, including sugars, organic acids, and amino acids; however, their content is …

Statistical methods and resources for biomarker discovery using metabolomics

NR Anwardeen, I Diboun, Y Mokrab, AA Althani… - BMC …, 2023 - Springer
Metabolomics is a dynamic tool for elucidating biochemical changes in human health and
disease. Metabolic profiles provide a close insight into physiological states and are highly …

Metabolomics as a valid analytical technique in environmental exposure research: application and progress

S Wei, Y Wei, Y Gong, Y Chen, J Cui, L Li, H Yan, Y Yu… - Metabolomics, 2022 - Springer
Background In recent years, studies have shown that exposure to environmental pollutants
(eg, radiation, heavy metal substances, air pollutants, organic pollutants) is a leading cause …

[HTML][HTML] Spatial single cell metabolomics: current challenges and future developments

KDG Saunders, HM Lewis, DJV Beste, O Cexus… - Current opinion in …, 2023 - Elsevier
Single cell metabolomics is a rapidly advancing field of bio-analytical chemistry which aims
to observe cellular biology with the greatest detail possible. Mass spectrometry imaging and …

Metabolomic approaches to investigate the effect of metformin: an overview

HW Kim - International journal of molecular sciences, 2021 - mdpi.com
Metformin is the first-line antidiabetic drug that is widely used in the treatment of type 2
diabetes mellitus (T2DM). Even though the various therapeutic potential of metformin …

Approaches in metabolomics for regulatory toxicology applications

E Olesti, V González-Ruiz, MF Wilks, J Boccard… - Analyst, 2021 - pubs.rsc.org
Innovative methodological approaches are needed to conduct human health and
environmental risk assessments on a growing number of marketed chemicals. Metabolomics …