Autoimmune heparin‐induced thrombocytopenia (aHIT) indicates the presence in patients of
anti‐platelet factor 4 (PF4)–polyanion antibodies that are able to activate platelets strongly …

Traditional vaccines, based on the administration of killed or attenuated microorganisms,
have proven to be among the most effective methods for disease prevention. Safety issues …

Despite advances in critical care medicine, infection remains a significant problem that
continues to be complicated with the challenge of antibiotic resistance …

ABSTRACT Toll-like receptor 3 (TLR3) is a pattern recognition receptor that senses
exogenous (viral) as well as endogenous (mammalian) double-stranded RNA in …

Abstract Double-stranded RNA (dsRNA), the genetic material for many RNA viruses,
induces robust host immune responses via pattern recognition receptors, which include Toll …

The development of an effective multivalent vaccine against SARS-CoV-2 variants is an
important means to improve the global public health situation caused by COVID-19. In this …

Aims Acute lung inflammation, particularly acute respiratory distress syndrome (ARDS), is
caused by a variety of pathogens including bacteria and viruses. β-Glucans have been …

Abstract Alternaramide (1), a novel lipophilic depsipeptide, has been isolated from the
extract of the marine-derived fungus Alternaria sp. SF-5016. In the course of extensive …

The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant
immune responses in cancer patients has been extensively investigated throughout the past …

Hepatitis B virus (HBV) as the main prevalent infectious agent, play important roles in
inducing severe liver diseases. Previous studies demonstrated that during prolonged forms …