Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases
Mast cells have crucial roles in allergic and other inflammatory diseases. Preclinical
approaches provide circumstantial evidence for mast cell involvement in many diseases, but …
approaches provide circumstantial evidence for mast cell involvement in many diseases, but …
[HTML][HTML] New insights into the pathogenesis of bullous pemphigoid: 2019 update
G Genovese, G Di Zenzo, E Cozzani, E Berti… - Frontiers in …, 2019 - frontiersin.org
There are several lines of evidence indicating that the physiopathological bases of bullous
pemphigoid (BP), the most common subepidermal autoimmune bullous disease, are …
pemphigoid (BP), the most common subepidermal autoimmune bullous disease, are …
[HTML][HTML] Epidermolysis bullosa acquisita: the 2019 update
H Koga, C Prost-Squarcioni, H Iwata… - Frontiers in …, 2019 - frontiersin.org
Epidermolysis bullosa acquisita (EBA) is an orphan autoimmune disease. Patients with EBA
suffer from chronic inflammation as well as blistering and scarring of the skin and mucous …
suffer from chronic inflammation as well as blistering and scarring of the skin and mucous …
[HTML][HTML] The role of eosinophils in bullous pemphigoid: a developing model of eosinophil pathogenicity in mucocutaneous disease
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant
mortality and morbidity. While historically BP has been characterized as an IgG driven …
mortality and morbidity. While historically BP has been characterized as an IgG driven …
[HTML][HTML] Bidirectional mast cell–eosinophil interactions in inflammatory disorders and cancer
MR Galdiero, G Varricchi, M Seaf, G Marone… - Frontiers in …, 2017 - frontiersin.org
Human mast cells (MCs) and eosinophils were first described and named by Paul Ehrlich.
These cells have distinct myeloid progenitors and differ morphologically, ultrastructurally …
These cells have distinct myeloid progenitors and differ morphologically, ultrastructurally …
Review of autoimmune blistering diseases: the Pemphigoid diseases
BS Daniel, DF Murrell - Journal of the European Academy of …, 2019 - Wiley Online Library
Abstract Autoimmune Blistering Diseases of the Pemphigoid type is characterised by sub‐
epidermal blisters (SEB) with circulating autoantibodies against components of the …
epidermal blisters (SEB) with circulating autoantibodies against components of the …
[HTML][HTML] Current clinical trials in pemphigus and pemphigoid
Autoimmune bullous dermatoses (AIBDs) are a group of rare chronic inflammatory skin
diseases, which clinically manifest as blisters and erosions of the skin and/or mucosa …
diseases, which clinically manifest as blisters and erosions of the skin and/or mucosa …
[HTML][HTML] BP180 is critical in the autoimmunity of bullous pemphigoid
Bullous pemphigoid (BP) is by far the most common autoimmune blistering dermatosis that
mainly occurs in the elderly. The BP180 is a transmembrane glycoprotein, which is highly …
mainly occurs in the elderly. The BP180 is a transmembrane glycoprotein, which is highly …
Targeted therapies for autoimmune bullous diseases: current status
KT Amber, R Maglie, F Solimani, R Eming, M Hertl - Drugs, 2018 - Springer
Autoimmune bullous skin disorders are rare but meaningful chronic inflammatory diseases,
many of which had a poor or devastating prognosis prior to the advent of …
many of which had a poor or devastating prognosis prior to the advent of …
Risk of incident venous thromboembolism among patients with bullous pemphigoid or pemphigus vulgaris: a nationwide cohort study with meta‐analysis
Background Bullous pemphigoid (BP) and pemphigus vulgaris (PV) share similar
pathophysiology with venous thromboembolism (VTE) involving platelet activation, immune …
pathophysiology with venous thromboembolism (VTE) involving platelet activation, immune …