[HTML][HTML] The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies
Mesenchymal stem cells (MSCs) have been identified in many adult tissues. MSCs can
regenerate through cell division or differentiate into adipocytes, osteoblasts and …
regenerate through cell division or differentiate into adipocytes, osteoblasts and …
Effects of oxidative stress on mesenchymal stem cell biology
RA Denu, P Hematti - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Mesenchymal stromal/stem cells (MSCs) are multipotent stem cells present in most fetal and
adult tissues. Ex vivo culture‐expanded MSCs are being investigated for tissue repair and …
adult tissues. Ex vivo culture‐expanded MSCs are being investigated for tissue repair and …
SIRT6, a mammalian deacylase with multitasking abilities
AR Chang, CM Ferrer… - Physiological …, 2020 - journals.physiology.org
Mammalian sirtuins have emerged in recent years as critical modulators of multiple
biological processes, regulating cellular metabolism, DNA repair, gene expression, and …
biological processes, regulating cellular metabolism, DNA repair, gene expression, and …
[HTML][HTML] Mitochondrial transfer and regulators of mesenchymal stromal cell function and therapeutic efficacy
A Mohammadalipour, SP Dumbali… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the microenvironment in
both normal physiology and disease. While MSCs predominantly utilize glycolysis in their …
both normal physiology and disease. While MSCs predominantly utilize glycolysis in their …
SIRT6: novel mechanisms and links to aging and disease
SIRT6, a member of the Sirtuin family of NAD+-dependent enzymes, has established roles in
chromatin signaling and genome maintenance. Through these functions, SIRT6 protects …
chromatin signaling and genome maintenance. Through these functions, SIRT6 protects …
Emerging roles of SIRT6 in human diseases and its modulators
The biological functions of sirtuin 6 (SIRT6; eg, deacetylation, defatty‐acylation, and mono‐
ADP‐ribosylation) play a pivotal role in regulating lifespan and several fundamental …
ADP‐ribosylation) play a pivotal role in regulating lifespan and several fundamental …
Metformin for cardiovascular protection, inflammatory bowel disease, osteoporosis, periodontitis, polycystic ovarian syndrome, neurodegeneration, cancer …
M Ala, M Ala - ACS pharmacology & translational science, 2021 - ACS Publications
Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …
Emerging therapeutic potential of SIRT6 modulators
Sirtuin 6 (SIRT6) is an NAD+-dependent protein deacylase and mono-ADP-
ribosyltransferase of the sirtuin family with a wide substrate specificity. In vitro and in vivo …
ribosyltransferase of the sirtuin family with a wide substrate specificity. In vitro and in vivo …
Sirtuin 6 expression and inflammatory activity in diabetic atherosclerotic plaques: effects of incretin treatment
The role of sirtuin 6 (SIRT6) in atherosclerotic progression of diabetic patients is unknown.
We evaluated SIRT6 expression and the effect of incretin-based therapies in carotid plaques …
We evaluated SIRT6 expression and the effect of incretin-based therapies in carotid plaques …
Mitochondria in mesenchymal stem cell biology and cell therapy: from cellular differentiation to mitochondrial transfer
YC Hsu, YT Wu, TH Yu, YH Wei - Seminars in cell & developmental biology, 2016 - Elsevier
Mesenchymal stem cells (MSCs) are characterized to have the capacity of self-renewal and
the potential to differentiate into mesoderm, ectoderm-like and endoderm-like cells. MSCs …
the potential to differentiate into mesoderm, ectoderm-like and endoderm-like cells. MSCs …