Diabetic retinopathy (DR) causes significant visual loss on a global scale. Treatments for the
vision-threatening complications of diabetic macular edema (DME) and proliferative diabetic …

This review summarizes the pathological features of diabetic retinopathy. The lesions
occurring in the diabetic retina have been described over many decades using descriptive …

Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Purpose: We quantified retinal and choriocapillaris microvascular changes in healthy control
eyes and different stages of diabetic retinopathy (DR) using optical coherence tomography …

Recent evidence suggests that capillary pericytes are contractile and play a crucial role in
the regulation of microcirculation. However, failure to detect components of the contractile …

Resident microglial cells can be regarded as the immunological watchdogs of the brain and
the retina. They are active sensors of their neuronal microenvironment and rapidly respond …

The ang opoietin/t yrosine kinase with i mmunoglobulin and e pidermal growth factor
homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development …

Diabetic retinopathy remains a relevant clinical problem. In parallel with diagnostic and
therapeutic improvements, the role of glycaemia and reactive metabolites causing cell stress …